婴幼儿颌面血管瘤浅表 X 射线治疗的短期疗效。

Short-term efficacy of superficial X-ray treatment for infantile maxillofacial hemangioma.

机构信息

Dept. of Dermatology, Sichuan Academy of Medical Sciences & Sichuan Provincial People,s Hospital, Chengdu 610072, China.

School of Management and Economics, University of Electronic Science and Technology of China, Chengdu 611731, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Aug 1;39(4):464-468. doi: 10.7518/hxkq.2021.04.014.

DOI:10.7518/hxkq.2021.04.014

PMID:34409804

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8381126/

Abstract

OBJECTIVES

This study aimed to explore the short-term clinical efficacy and factors influencing low-dose superficial X-ray for treating infantile maxillofacial hemangioma.

METHODS

Retrospective analysis was conducted on 161 cases of infants with maxillofacial hemangioma treated with superficial X-ray in the Laser Center of Dermatology Department of Sichuan Provincial People's Hospital from January 2015 to December 2017. Clinical efficacy was analyzed by comparing the photos before and after treatment. Patients were further divided into groups according to different genders, age at the start of treatment, preterm birth or low birth weight, hemangioma site, longest diameter of hemangioma, and type of hemangioma to analyze whether differences existed in clinical efficacy and therapeutic dose between different groups.

RESULTS

Twelve months after the end of treatment, the overall cure rate was 93.8%, and the significant efficiency was 97.5%. The clinical efficacy was related to the age of children at the beginning of treatment and the type of hemangioma (<0.05). The clinical efficacy of children aged less than or equal to 12 months and superficial hemangioma group was better than that of children aged more than 12 months and deep subtype or mixed hemangioma group, respectively. Therapeutic doses associa-ted with hemangioma treatment with diameter, category, age (<0.05), diameter greater than or equal to 4 cm hemangioma group, the mixed type or deep in the group, the children older than 12 months hemangioma group, respectively, the dia-meter is less than 4 cm hemangioma, superficial hemangioma group and age less than or equal to 12 months hemangioma total treatment group exposure dose is greater.

CONCLUSIONS

Low-dose superficial X-ray is safe and effective for the treatment of infantile maxillofacial hemangioma. Age and type of hemangioma at the time of treatment are the factors influencing therapeutic dose and clinical efficacy.

摘要

目的

本研究旨在探讨低剂量浅表 X 射线治疗婴幼儿颌面血管瘤的短期临床疗效及其影响因素。

方法

回顾性分析 2015 年 1 月至 2017 年 12 月四川省人民医院皮肤科激光中心收治的 161 例颌面血管瘤患儿浅表 X 射线治疗的临床资料，比较治疗前后照片，分析疗效。根据患儿性别、治疗起始年龄、早产儿或低出生体重、血管瘤部位、血管瘤最长径、血管瘤类型分组，分析不同组间临床疗效和治疗剂量的差异。

结果

治疗结束后 12 个月，总有效率为 93.8%，显效率为 97.5%。临床疗效与患儿治疗起始年龄和血管瘤类型有关（<0.05）。起始年龄≤12 个月和浅表型患儿的临床疗效优于起始年龄>12 个月和深部型或混合性患儿。治疗剂量与瘤体直径、类别、年龄有关（<0.05），直径≥4cm 组、混合型或深部组、年龄>12 个月的患儿，瘤体直径<4cm 组、浅表型组、年龄≤12 个月的患儿，总治疗组的曝光剂量较大。