Department of Rheumatology, University of California San Diego, San Diego, California.
Department of Pediatric and Adolescent Dermatology, University of California San Diego, San Diego, California.
Birth Defects Res. 2017 Jul 3;109(11):809-815. doi: 10.1002/bdr2.1023. Epub 2017 Apr 12.
Infantile hemangiomas (IHs) are the most common vascular tumors in infants, appearing in early infancy and ultimately regressing with time. Clinical presentation may vary, with a minority of lesions causing impairment of vital function (e.g., respiratory or visual obstruction), permanent scarring, and/or disfigurement. The pathogenesis of IH is complex and poorly understood. Risk factors implicated in their development include preterm birth and placental anomalies. IH presents a myriad of clinical challenges, including correct diagnosis and whether or not to pursue treatment. This article is a review of the current literature regarding pathogenesis, clinical presentation, treatment, and prognosis of IH. Birth Defects Research 109:809-815, 2017. © 2017 Wiley Periodicals, Inc.
婴儿血管瘤（IHs）是婴儿中最常见的血管肿瘤，在婴儿早期出现，最终随时间而消退。临床表现可能有所不同，少数病变会导致重要功能受损（例如呼吸或视觉阻塞）、永久性瘢痕和/或畸形。IH 的发病机制复杂且尚未完全了解。其发生的危险因素包括早产和胎盘异常。IH 带来了诸多临床挑战，包括正确诊断以及是否进行治疗。本文综述了关于 IHs 的发病机制、临床表现、治疗和预后的现有文献。出生缺陷研究 109:809-815, 2017。© 2017 Wiley Periodicals, Inc.
