Laboratory of Medical Mycology and Space Environmental Medicine, School of Medicine, Graduate School of Medicine, Teikyo University, 2-11-1 Kaga, Itabashi, Tokyo, 173-8605, Japan.
Department of AMR Mycosis Control Research in the Environment of Treatment and Education for Physically and Mentally Handicapped Persons, School of Medicine, Teikyo University, 2-11-1 Kaga, Itabashi, Tokyo, Japan.
Mycopathologia. 2021 Dec;186(6):871-876. doi: 10.1007/s11046-021-00581-x. Epub 2021 Aug 19.
The prevalence of fungal otitis externa, or otomycosis, has been increasing in recent decades. Fungi may act as primary pathogens in this condition, or they may occur as secondary infections after prolonged ototopical treatment with antibiotics, which alters the flora of the external auditory canal (EAC) and enables overgrowth of its fungal inhabitants. We report here a case of otomycosis by Candida parapsilosis, Malassezia obtusa, and Malassezia furfur as a secondary infection following prolonged otic ofloxacin treatment. To the best of our knowledge, although isolation of C. parapsilosis and M. furfur from the EAC is not uncommon, the recovery of M. obtusa has not yet been reported. We also conducted a literature review of the searchable data on PubMed concerning the isolation of Malassezia species from the human EAC.
近年来，真菌性外耳炎（耳霉菌病）的患病率一直在上升。真菌可能在这种情况下作为原发性病原体起作用，或者在经过抗生素的长期耳局部治疗后，作为继发性感染发生，这种治疗改变了外耳道（EAC）的菌群，使真菌过度生长。我们在此报告一例由近平滑念珠菌、钝形厚壁孢子菌和糠秕马拉色菌引起的耳霉菌病，这是在长期使用氧氟沙星滴耳液治疗后的继发感染。据我们所知，尽管从 EAC 分离出近平滑念珠菌和糠秕马拉色菌并不罕见，但尚未报道从 EAC 中分离出钝形厚壁孢子菌。我们还对 PubMed 上可搜索的数据进行了文献回顾，以了解有关从人类 EAC 分离出马色菌属物种的信息。
