National Taiwan University.
Oncol Nurs Forum. 2021 Sep 1;48(5):558-576. doi: 10.1188/21.ONF.558-576.
Cancer-related fatigue (CRF) substantially affects daily living and quality of life, but objective CRF measures remain limited. This review aimed to identify the correlation between muscle strength and body composition measures and CRF, as well as potential objective indicators for assessing CRF.
PubMed®, MEDLINE®, CINAHL®/PsycINFO®, and Embase® were searched for studies published from January 2000 to January 2021.
Study selection and quality assessment were conducted using the Critical Appraisals Skills Programme checklist and the Strengthening the Reporting of Observational Studies in Epidemiology statement. Comprehensive Meta-Analysis software was used to perform meta-analysis.
25 studies were selected, and 19 measures were analyzed. CRF negatively correlated with hand grip strength, knee extensor strength, and the sit-to-stand test. No significant correlation was found between body composition measures and CRF.
The evidence suggests that muscle strength measures may be potential indicators for CRF assessment. Combining objective and subjective CRF assessments could assist clinicians in evaluating the effectiveness of CRF interventions more accurately.
癌症相关疲劳（CRF）会严重影响日常生活和生活质量，但客观的 CRF 测量方法仍然有限。本综述旨在确定肌肉力量和身体成分测量与 CRF 之间的相关性，以及评估 CRF 的潜在客观指标。
从 2000 年 1 月至 2021 年 1 月，在 PubMed®、MEDLINE®、CINAHL®/PsycINFO®和 Embase®上搜索研究。
使用关键评估技能计划清单和观察性研究的强化报告标准进行研究选择和质量评估。综合荟萃分析软件用于进行荟萃分析。
选择了 25 项研究，并分析了 19 项指标。CRF 与握力、膝关节伸肌力量和坐立试验呈负相关。身体成分测量与 CRF 之间没有显著相关性。
证据表明，肌肉力量测量可能是 CRF 评估的潜在指标。结合客观和主观的 CRF 评估可以帮助临床医生更准确地评估 CRF 干预措施的效果。
