Minasyan S M, Baklavadzhyan O G
Department of Human and Animal Physiology, State University, Erevan.
Neurosci Behav Physiol. 1987 Nov-Dec;17(6):531-8. doi: 10.1007/BF01186354.
Phasic changes in the bioelectrical activity of the dorsal hippocampus (field CA3), the mesencephalic reticular formation, and several regions of the neocortex and the reticulo-cortical evoked potentials were measured under conditions of the action of prolonged vibration (3 months) in electrophysiological experiments with rabbits. Daily three-hour vibration during the first month of the experiment evoked an activation reaction in the EEG, characterized by a desynchronization effect in the neocortex and hippocampus and by the stabilization of the v rhythm in the mesencephalic reticular formation. Noted against this background was a certain facilitation in the reticulo-cortical evoked potentials, more pronounced in the neocortex, and a decline in the ascending activational influence of the mesencephalic reticular formation. The three-month action of vibration exerted an inhibitory influence on reticulo-cortical interrelationships, expressed in a decline in the compound bioelectrical activity of the cortex and subcortical formations, the excitability of the mesencephalic reticular formation, and the suppression of reticulo-cortical evoked potentials. At the same time an elongation of the latent periods of the positive phases of the evoked potentials, a decline in their amplitude, and a reduction of the negative phase in limbic structures was noted. The question of the physiological mechanism of development of vibrational pathology is discussed.
在对家兔进行的电生理实验中，在长时间振动（3个月）作用的条件下，测量了背侧海马体（CA3区）、中脑网状结构、新皮质的几个区域以及网状结构 - 皮质诱发电位的生物电活动的阶段性变化。在实验的第一个月，每天3小时的振动在脑电图中引发了一种激活反应，其特征是新皮质和海马体出现去同步化效应，中脑网状结构的v节律稳定。在此背景下，网状结构 - 皮质诱发电位有一定程度的易化，在新皮质中更为明显，同时中脑网状结构的上行激活影响下降。振动3个月的作用对网状结构 - 皮质的相互关系产生了抑制作用，表现为皮质和皮质下结构的复合生物电活动下降、中脑网状结构的兴奋性下降以及网状结构 - 皮质诱发电位的抑制。同时，观察到诱发电位正相潜伏期延长、幅度下降以及边缘结构中负相减小。文中讨论了振动性病理发展的生理机制问题。
