Department of Orthopaedic Surgery, University of Saarland, Germany.
Chair of Mechanics and Robotics, University of Duisburg-Essen, Germany.
Clin Biomech (Bristol). 2021 Aug;88:105445. doi: 10.1016/j.clinbiomech.2021.105445. Epub 2021 Aug 5.
Impacts, traumas and strokes are spontaneously life-threatening, but chronic symptoms strangle patient every day. Colorectal tissue mechanics in such chronic situations not only regulates the physio-psychological well-being of the patient, but also confirms the level of comfort and post-operative clinical outcomes. Numerous uniaxial and multiaxial tensile experiments on healthy and affected samples have evidenced significant differences in tissue mechanical behavior and strong colorectal anisotropy across each layer in thickness direction and along the length. Furthermore, this study reviewed various forms of passive constitutive models for the highly fibrous colorectal tissue ranging from the simplest linearly elastic and the conventional isotropic hyperelastic to the most sophisticated second harmonic generation image based anisotropic mathematical formulation. Under large deformation, the isotropic description of tissue mechanics is unequivocally ineffective which demands a microstructural based tissue definition. Therefore, the information collected in this review paper would present the current state-of-the-art in colorectal biomechanics and profoundly serve as updated computational resources to develop a sophisticated characterization of colorectal tissues.
冲击、外伤和中风是自发的危及生命的，但慢性症状每天都在扼杀患者。在这种慢性情况下，结肠直肠组织力学不仅调节着患者的生理心理幸福感，而且还证实了舒适度和术后临床结果的水平。对健康和患病样本进行的大量单轴和多轴拉伸实验表明，组织力学行为存在显著差异，并且在厚度方向的每个层和沿长度方向的结肠直肠各向异性很强。此外，本研究回顾了各种形式的用于高度纤维状结肠直肠组织的被动本构模型，从最简单的线性弹性和传统各向同性超弹性到最复杂的基于二次谐波生成图像的各向异性数学公式。在大变形下，组织力学的各向同性描述显然是无效的，这需要基于微观结构的组织定义。因此，本文收集的信息将呈现结肠直肠生物力学的最新现状，并作为更新的计算资源，为结肠直肠组织的复杂特征提供支持。
