Pattan, MD, Division of Endocrinology, Wyoming Medical Center, Casper, Wyoming, USA. Singh, MD, MS, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA. Abdelmoneim, MD, MSc, MS, Research Collaborator, Cardiovascular Ultrasound Imaging and Hemodynamic Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA. Gopinath, MD, Department of Internal Medicine, University of Kansas, Wichita, Kansas, USA. Sundaresh, MD, MS, Division of Endocrinology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Psychopharmacol Bull. 2021 Jun 1;51(3):65-71.
Lithium is the gold standard treatment for bipolar disorder. Studies have shown an association between lithium and hyperparathyroidism. However, there is limited data regarding the management of lithium-induced hyperparathyroidism. We present a clinical conundrum which physicians frequently encounter-an excellent lithium responder refractory to other treatments who developed lithium-induced hyperparathyroidism. Medical treatment with cinacalcet was successful in management of hyperparathyroidism without discontinuing lithium maintenance therapy.
锂是双相情感障碍的金标准治疗方法。研究表明锂与甲状旁腺功能亢进之间存在关联。然而,关于锂诱导的甲状旁腺功能亢进的管理,数据有限。我们提出了一个临床难题,这是医生经常遇到的情况——一个对其他治疗方法有反应但锂治疗无效的优秀锂反应者,发展为锂诱导的甲状旁腺功能亢进。使用西那卡塞进行药物治疗成功地控制了甲状旁腺功能亢进,而无需停止锂维持治疗。