Schraier M, Guinsburg R, Waldbaum C, Valguarnera J, Cueva F
Hospital Israelita Ezrah, Seccion de Gastroenterología, Buenos Aires, Argentina.
Acta Gastroenterol Latinoam. 1987;17(2):73-84.
We intended to estimate D.G.R. in patients suffering from GU, and CG, comparing them with healthy controls. 70 patients, divided in 3 groups, were studied; Group A (Control): 14 cases, Group B (GU) type I Johnson: 11 cases, type III Johnson: 20 cases; Group C (CG): 25 cases (11 antral and 14 antral and fundic). The following studies were performed in all of them upper digestive tract X-ray and fibro-endoscopy with multiple antral and fundic biopsies. Tc 99 HIDA 2 ml. Cu. I.V. was used as radioactive compound, and in the first hour 0.3 ml Cu. in 100 cc of water was administered orally, so as to confirm gastric topography. All patients were studied for 2 hour. Quantitative assessment of D.G.R. was expressed in % related to the hepatobiliary area. D.G.R. was detected in 7.1% of patients in Group A: 54.5% of GU type I and 70% in GU type III. In antral CG a 72.7% of D.G.R. was observed and in antral and fundic CG a 87.6% was found. The differences were significant in all the cases. D.G.R. MAGNITUDE, expressed as geometric mean, was: for Group A: 0.73%; for Group B: Ulcer type I: 6.26% and type III: 6.26%, for Group C: 6.78% in antral gastritis and 11.41% in antral and fundic gastritis.
我们旨在评估患有胃溃疡（GU）和慢性胃炎（CG）的患者的胆汁反流率（D.G.R.），并将其与健康对照组进行比较。我们研究了70例患者，分为3组；A组（对照组）：14例，B组（GU）：I型约翰逊溃疡11例，III型约翰逊溃疡20例；C组（CG）：25例（11例胃窦部和14例胃窦部及胃底部）。对所有患者均进行了以下检查：上消化道X线检查和纤维内镜检查，并取多处胃窦部和胃底部组织进行活检。使用2毫升锝99 - 亚氨基二乙酸（Tc 99 HIDA）静脉注射作为放射性化合物，并在第一小时口服0.3毫升该化合物溶于100毫升水中的溶液，以确认胃的形态。所有患者均研究2小时。D.G.R.的定量评估以与肝胆区域相关的百分比表示。在A组患者中检测到7.1%的胆汁反流率；I型GU患者中为54.5%，III型GU患者中为70%。在胃窦部CG患者中观察到72.7%的胆汁反流率，在胃窦部及胃底部CG患者中发现87.6%的胆汁反流率。所有病例中的差异均具有统计学意义。以几何平均数表示的D.G.R.幅度为：A组：0.73%；B组：I型溃疡为6.26%，III型溃疡为6.26%；C组：胃窦部胃炎为6.78%，胃窦部及胃底部胃炎为11.41%。
