Albany Medical College, Albany NY and University of New Mexico, Albuquerque, NM, USA.
, 391 Myrtle Avenue, Suite 200, Albany, NY, 12208, USA.
Int Urogynecol J. 2022 Jan;33(1):115-122. doi: 10.1007/s00192-021-04954-0. Epub 2021 Aug 25.
The objective was to compare body image and sexual activity and function changes up to 3 years after sacrospinous ligament fixation with graft hysteropexy or vaginal hysterectomy with uterosacral ligament suspension (hysterectomy).
This was a planned secondary analysis of a multi-center randomized trial of women undergoing prolapse repair with mesh hysteropexy versus hysterectomy. Women were masked to intervention. The modified Body Image Scale (BIS), sexual activity status, and Pelvic Organ Prolapse/Incontinence Sexual Questionnaire, IUGA-Revised (PISQ-IR) scores were reported at baseline and 1.5, 6, 12, 18, 24, and 36 months after surgery. We compared mean BIS and PISQ-IR scores, the proportion of women whose BIS scores met a distribution-based estimate of the minimally important difference (MID), and sexual activity status. Comparisons were analyzed with linear and logistic repeated measures models adjusted for site, intervention, visit, and intervention by visit interaction.
Eighty-eight women underwent mesh hysteropexy; 87 underwent hysterectomy. Women were similar with regard to baseline characteristics, mean age 65.9 ± 7.3 years, and most had stage III or IV prolapse (81%). Baseline mean BIS scores were not significantly different, improved in both groups by 1.5 months, and were sustained through 36 months with no differences between groups (all p > 0.05). The estimated BIS MID was 3; and by 36 months, more women in the mesh hysteropexy group achieved the MID than in the hysterectomy group (62% vs 44%, p = 0.04). The makeup of the sexually active cohort changed throughout the study, making function comparisons difficult.
Body image improves following prolapse surgery whether or not hysterectomy is performed or transvaginal mesh is used at the time of repair; sexual activity status changes over time following prolapse surgery.
本研究旨在比较骶棘韧带固定术联合悬吊带(子宫切除术)与阴道子宫切除术联合子宫骶骨悬韧带固定术(子宫切除术)后 3 年内的身体意象和性活动及功能变化。
这是一项多中心随机试验的二次分析,该试验比较了网片悬吊带修补术与子宫切除术治疗脱垂的效果。患者对干预措施进行了分组。采用改良身体意象量表(BIS)、性活动状态以及盆腔器官脱垂/尿失禁性问卷(PISQ-IR)评分在基线和手术后 1.5、6、12、18、24 和 36 个月进行评估。我们比较了 BIS 和 PISQ-IR 评分的平均值、达到基于分布的最小有意义差异(MID)估计值的 BIS 评分女性比例以及性活动状态。采用线性和逻辑重复测量模型进行分析,调整了地点、干预措施、访视和干预措施访视交互作用。
88 例患者行网片悬吊带修补术,87 例行子宫切除术。两组患者基线特征相似,平均年龄 65.9±7.3 岁,大多数患者为 III 期或 IV 期脱垂(81%)。基线时 BIS 评分无显著差异,两组患者在 1.5 个月时均得到改善,并在 36 个月时持续改善,两组间无差异(均 p>0.05)。BIS 的估计 MID 为 3;36 个月时,网片悬吊带修补术组达到 MID 的患者多于子宫切除术组(62%比 44%,p=0.04)。随着研究的进行,性活跃队列的组成发生了变化,使得功能比较变得困难。
无论是否行子宫切除术或在修复时是否使用阴道网片,脱垂手术后身体意象都会得到改善;脱垂手术后性活动状态会随时间而变化。