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现在无法溶解我:一例由新冠病毒引发的静脉血栓栓塞症对阿哌沙班产生耐药:病例报告

Can't Dissolve Me Now: A COVID-19 Provoked Venous Thromboembolism Breaks Through Apixaban: Case Report.

作者信息

Arena Alexander W, Hussein Ahmad, Kurkowski Ellen J, Kulkarni Miriam L

机构信息

St. John's Riverside Hospital, Department of Emergency Medicine, Yonkers, New York.

出版信息

Clin Pract Cases Emerg Med. 2021 May;5(2):202-205. doi: 10.5811/cpcem.2021.3.50505.

Abstract

INTRODUCTION

Coronavirus disease 2019 (COVID-19) is a multisystem process with a growing evidence of its endotheliopathy effects, with subsequent hypercoagulability states.

CASE REPORT

WWe present an emergency department case of a COVID-19-provoked deep venous thrombosis and pulmonary embolism without a history of venous thromboembolism (VTE), with extension of the VTE despite adherence to apixaban.

CONCLUSION

This case demonstrates the importance of further research and protocols for optimal dosage and treatment to prevent worsening VTE in COVID-19 patients.

摘要

引言

2019冠状病毒病(COVID-19)是一个多系统过程,越来越多的证据表明其存在内皮病变效应,并随后出现高凝状态。

病例报告

我们介绍一例急诊科病例,一名COVID-19引发的深静脉血栓形成和肺栓塞患者,既往无静脉血栓栓塞(VTE)病史,尽管坚持使用阿哌沙班,但VTE仍有进展。

结论

本病例表明,进一步研究以及制定关于最佳剂量和治疗的方案对于预防COVID-19患者VTE恶化具有重要意义。

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