Consorcio Corporación Sanitaria Parc Tauli, 08208 Sabadell, Spain.
Departamento de Psiquiatría y Medicina Legal, Universitat Autònoma de Barcelona, Bellaterra, 08193 Barcelona, Spain.
Genes (Basel). 2021 Jul 21;12(8):1108. doi: 10.3390/genes12081108.
The aim of this research is to analyze the relationship between executive functions and adaptive behavior in girls with Fragile X syndrome (FXS) in the school setting. This study is part of a larger investigation conducted at the Hospital Parc Tauli in Sabadell. The sample consists of a total of 40 girls (26 with FXS and 14 control) aged 7-16 years, who were administered different neuropsychological tests (WISC-V, NEPSY-II, WCST, TOL) and questionnaires answered by teachers (ABAS-II, BRIEF 2, ADHD Rating Scale). The results show that there is a greater interaction between some areas of executive function (cognitive flexibility, auditory attention, and visual abstraction capacity) and certain areas of adaptive behavior (conceptual, practical, social, and total domains) in the FXS group than in the control group. These results suggest that an alteration in the executive functions was affecting the daily functioning of the girls with FXS to a greater extent.
本研究旨在分析学校环境中脆性 X 综合征（FXS）女孩的执行功能与适应行为之间的关系。该研究是在萨瓦德尔的 Parc Tauli 医院进行的更大规模调查的一部分。样本包括共 40 名女孩（26 名患有 FXS，14 名对照），年龄在 7-16 岁之间，她们接受了不同的神经心理学测试（WISC-V、NEPSY-II、WCST、TOL）和由教师回答的问卷（ABAS-II、BRIEF 2、ADHD 评定量表）。结果表明，在 FXS 组中，一些执行功能领域（认知灵活性、听觉注意力和视觉抽象能力）与某些适应行为领域（概念、实践、社会和总体领域）之间的相互作用大于对照组。这些结果表明，执行功能的改变对 FXS 女孩的日常生活功能有更大的影响。
