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2019冠状病毒病大流行期间炎症性肠病患者的社交距离措施

Social Distancing during COVID-19 Pandemic among Inflammatory Bowel Disease Patients.

作者信息

Łodyga Michał, Maciejewska Katarzyna, Eder Piotr, Waszak Katarzyna, Stawczyk-Eder Kamila, Dobrowolska Agnieszka, Kaczka Aleksandra, Gąsiorowska Anita, Stępień-Wrochna Beata, Cicha Małgorzata, Rydzewska Grażyna

机构信息

Department of Gastroenterology with the Inflammatory Bowel Disease Subdivision, Central Clinical Hospital of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.

Department of Gastroenterology, Dietetics and Internal Medicine, Poznań University of Medical Sciences, Heliodor Święcicki University Hospital, 60-355 Poznań, Poland.

出版信息

J Clin Med. 2021 Aug 20;10(16):3689. doi: 10.3390/jcm10163689.

Abstract

(1) Background: Social distancing rules have been widely introduced in the fight against the coronavirus disease 2019 (COVID-19) pandemic. So far, the effectiveness of these methods has not been assessed in the group of inflammatory bowel disease (IBD) patients. (2) Methods: The study included 473 patients with IBD who made 1180 hospital visits from 1 May to 30 September 2020. During each visit, the patients completed a five-step, progressive scale that was developed to assess the degree of social isolation. In parallel, other demographic data were collected and the concentrations of anti-severe acute respiratory coronavirus 2 (SARS-CoV-2) IgG and IgM+IgA antibodies were measured using the ELISA method. (3) Results: The study found a significant correlation between the degree of social distancing and the presence of anti-SARS-CoV-2 antibodies in the groups with the lowest degree of isolation (3 to 5). (4) Conclusions: Maintaining social distancing is an effective method for reducing the spread of SARS-CoV-2 virus among IBD patients.

摘要

(1) 背景:社交距离规则已在抗击2019冠状病毒病(COVID-19)大流行中广泛推行。迄今为止,这些方法的有效性尚未在炎症性肠病(IBD)患者群体中得到评估。(2) 方法:该研究纳入了473例IBD患者,他们在2020年5月1日至9月30日期间进行了1180次医院就诊。每次就诊时,患者完成一个为评估社交隔离程度而制定的五步渐进量表。同时,收集其他人口统计学数据,并使用酶联免疫吸附测定(ELISA)法测量抗严重急性呼吸综合征冠状病毒2(SARS-CoV-2)IgG和IgM+IgA抗体的浓度。(3) 结果:研究发现,在隔离程度最低(3至5级)的组中,社交距离程度与抗SARS-CoV-2抗体的存在之间存在显著相关性。(4) 结论:保持社交距离是减少SARS-CoV-2病毒在IBD患者中传播的有效方法。

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