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来自患有多囊肾病的已故供体的肾移植

Renal Transplantation from a Deceased Donor with Polycystic Kidney Disease.

作者信息

Tabbara Marina M, Guerra Giselle, Ciancio Gaetano

机构信息

Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, USA.

出版信息

Case Rep Transplant. 2021 Aug 16;2021:6711155. doi: 10.1155/2021/6711155. eCollection 2021.

Abstract

Renal transplantation is the gold standard treatment for patients with end-stage renal disease (ESRD) as it demonstrates improved long-term survival compared to patients who remain on renal replacement therapy. The widening gap between the demand and supply of organs warrants the expansion of donor criteria for renal transplantation. Kidneys with multiple cysts are often rejected for transplantation. Here, we present our recent experience of a 72-year-old patient with ESRD due to a biopsy-proven diabetic nephropathy who received a deceased donor kidney with adult polycystic kidney disease (APKD). At 31-month posttransplant, he had a serum creatinine of 1.6 mg/dL. Deceased donors affected by APKD should be considered an acceptable option for successful renal transplantation in select recipients, as well as an alternative kidney source to increase the donor pool.

摘要

肾移植是终末期肾病(ESRD)患者的金标准治疗方法,因为与接受肾脏替代治疗的患者相比,肾移植患者的长期生存率更高。器官供需差距不断扩大,这就需要扩大肾移植的供体标准。有多个囊肿的肾脏通常会被拒绝用于移植。在此,我们介绍我们最近的一例经验,一名72岁因活检证实为糖尿病肾病导致的ESRD患者,接受了一名患有成人多囊肾病(APKD)的已故供体的肾脏。移植后31个月,他的血清肌酐为1.6mg/dL。受APKD影响的已故供体应被视为特定受者成功进行肾移植的可接受选择,也是增加供体库的替代肾脏来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14e/8383719/1218b4594a78/CRIT2021-6711155.001.jpg

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