Gaston Fanny, Dupuy Nathalie, Girard-Perier Nina, Marque Sylvain R A, Dorey Samuel
Sartorius Stedim FMT S.A.S, Z.I. Les Paluds, Avenue de Jouques CS91051, CEDEX, 13781 Aubagne, France.
Aix Marseille Univ, Avignon Université, CNRS, IRD, IMBE, 13013 Marseille, France.
Polymers (Basel). 2021 Aug 10;13(16):2671. doi: 10.3390/polym13162671.
Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of irradiation induces the degradation and the release of chemicals able to spoil the biological solutions. Surprisingly, there are no investigations on multi-layer films combining multi-technique and multi-method approaches to unveil the events occurring during γ-irradiation. Furthermore, our investigations are focuses on properties/events occurring at product, macromolecular, and molecular levels.
几十年来，医用溶液的化学和生物安全储存一直是该行业日常关注的问题，在过去两年的大流行期间，这一问题显得尤为突出。通过γ辐照过程进行灭菌可轻松实现生物安全。然而，这种辐照会导致化学物质降解并释放出来，从而破坏生物溶液。令人惊讶的是，目前尚无关于结合多种技术和方法来揭示γ辐照过程中发生的事件的多层膜的研究。此外，我们的研究集中在产品、大分子和分子水平上发生的特性/事件。
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