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直肠出现类似增生性息肉的十二指肠型滤泡性淋巴瘤,同时在十二指肠和胃出现异时性病变。

A rare case of duodenal-type follicular lymphoma in rectum appearing as hyperplastic polyp with metachronous appearance in duodenum and stomach.

机构信息

Department of Gastroenterology, General Hospital of Nikea-Piraeus 'Agios Panteleimon', Athens, Greece.

Department of Pathology, General Hospital of Nikea-Piraeus 'Agios Panteleimon', Athens, Greece.

出版信息

Clin J Gastroenterol. 2021 Dec;14(6):1632-1636. doi: 10.1007/s12328-021-01501-8. Epub 2021 Aug 28.

DOI:10.1007/s12328-021-01501-8
PMID:34453280
Abstract

Hyperplastic polyps consist a very frequent finding in colonoscopy having a very low potential to malignancy. According to the international guidelines, it is recommended that all polyps should be resected except for diminutive (≤ 5 mm) rectal and rectosigmoid polyps which are predicted with confidence to be hyperplastic. Therefore, in departments where optical diagnosis can be ensured, a "resect and discard" strategy may be implemented for diminutive polyps. In our case, a duodenal-type follicular lymphoma was detected in a 5 mm rectum polyp with hyperplastic appearance. After 4 months, the lymphoma was detected also in stomach and duodenum. Under therapy with Rituximab, she is in remission. To our knowledge, there has never been reported such a case in the literature. Furthermore, it alerts us that we should be very cautious with the optical diagnosis and the "resect and discard strategy".

摘要

增生性息肉在结肠镜检查中是一种非常常见的发现,其恶性潜能非常低。根据国际指南,建议切除所有息肉,但直径小于 5 毫米的直肠和直肠乙状结肠息肉除外,这些息肉有信心被判断为增生性。因此,在能够保证光学诊断的科室,可以对小息肉实施“切除并丢弃”策略。在我们的病例中,在外观呈增生性的 5 毫米直肠息肉中发现了十二指肠型滤泡性淋巴瘤。4 个月后,在胃和十二指肠中也发现了淋巴瘤。在利妥昔单抗治疗下,她处于缓解期。据我们所知,这种情况在文献中从未有过报道。此外,这提醒我们,我们应该非常谨慎地进行光学诊断和“切除并丢弃”策略。

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