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在免疫治疗时代,外科医生在头颈部黏膜黑色素瘤的治疗中扮演什么角色?

What is the role of the surgeon in the management of head and neck mucosal melanoma in the immunotherapy era?

机构信息

University Hospitals Dorset NHS Foundation Trust, UK.

Cancer Sciences Division, University of Southampton, UK.

出版信息

Head Neck. 2021 Nov;43(11):3498-3503. doi: 10.1002/hed.26849. Epub 2021 Aug 28.

Abstract

INTRODUCTION

The advent of immunotherapy has impacted both the management and, to a lesser extent, the outcomes for patients with head and neck mucosal melanoma. As a consequence, one might expect that the role of the surgeon would be limited to the diagnostic work-up and that systemic therapies would be the mainstay of treatment.

METHODS AND RESULTS

Here, we present the surgical aspects of the recently published United Kingdom Head and Neck Mucosal Melanoma Guideline to highlight the continued role of surgeons in the management of this disease. We highlight key areas where surgeons remain the lead clinician and reinforce the multidisciplinary requirement for exemplary patient care.

CONCLUSIONS

Despite the advent of immunotherapy, surgeons continue to have a key role to play in this disease. When indicated, it is essential that appropriate surgery is offered by a suitably experienced team.

摘要

简介

免疫疗法的出现不仅影响了头颈部黏膜黑色素瘤患者的治疗管理,在一定程度上也影响了患者的预后。因此,人们可能会认为外科医生的作用仅限于诊断,而系统治疗将是治疗的主要手段。

方法和结果

在这里,我们介绍了最近发表的英国头颈部黏膜黑色素瘤指南中的手术方面,以强调外科医生在这种疾病管理中的持续作用。我们强调了外科医生仍然是主要临床医生的关键领域,并强调了多学科治疗以提供出色的患者护理的必要性。

结论

尽管免疫疗法已经问世,但外科医生在这种疾病中仍然发挥着关键作用。在有指征的情况下,由经验丰富的团队提供适当的手术至关重要。

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