Department of Chemistry, Yildiz Technical University, Davutpasa Campus, Istanbul 34220, Turkey.
Department of Materials Science, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Jan 5;264:120294. doi: 10.1016/j.saa.2021.120294. Epub 2021 Aug 21.
This study aimed for the development of a cost effective and efficient method for L-cysteine detection, without employing expensive instrumentation within a short analysis time. The proposed method has been involved in the photochemical preparation of gold nanoparticles and gold nanoparticles on graphene oxide nanostructures. The gold nanoparticles and gold nanoparticles on graphene oxide acted as simple and sensitive nano-sensors for L-cysteine, due to the molecular structure of the L-cysteine presented -NH and -SH, which is very attractive for coordination to gold nanoparticles and crosslink gold nanoparticles causing aggregation and color change. By using the gold nanoparticles on graphene oxide as a probe, the colorimetric detection of L-cysteine in a nanomolar order concentration was demonstrated.
本研究旨在开发一种经济高效的方法来检测 L-半胱氨酸，无需在短分析时间内使用昂贵的仪器。该方法涉及到金纳米粒子和氧化石墨烯纳米结构上的金纳米粒子的光化学制备。由于 L-半胱氨酸的分子结构呈现出 -NH 和 -SH，这对于与金纳米粒子配位以及交联金纳米粒子导致聚集和颜色变化非常有吸引力，因此金纳米粒子和氧化石墨烯上的金纳米粒子可用作 L-半胱氨酸的简单而灵敏的纳米传感器。通过使用氧化石墨烯上的金纳米粒子作为探针，成功地在纳摩尔级浓度下实现了 L-半胱氨酸的比色检测。
