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早发性脊柱侧凸中交界性后凸的患病率:在最终融合时能否纠正?

Prevalence of junctional kyphosis in early-onset scoliosis: can it be corrected at final fusion?

机构信息

Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE, 19803, USA.

Department of Orthopedics and Traumatology, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey.

出版信息

Eur Spine J. 2021 Dec;30(12):3563-3569. doi: 10.1007/s00586-021-06968-0. Epub 2021 Aug 28.

DOI:10.1007/s00586-021-06968-0
PMID:34455481
Abstract

PURPOSE

To investigate the risk and predictive factors of junctional issues after conversion from Traditional growing rod (TGR) to definitive spinal fusion in Early-onset scoliosis (EOS).

METHODS

Retrospective review of a multicenter EOS database. TGR patients who received final fusion with at least two-year follow-up were included. Proximal (PJA) and Distal junctional angles (DJA) on pre-final fusion, post-final fusion (within one year of surgery), and at latest follow-up were measured on lateral upright spinal radiographs. Differences in values among designated time points and predictive factors of junctional issues were evaluated statistically.

RESULTS

Forty-six of 251 patients (28 females, 18 males and mean age at final fusion: 12 ± 2 [9-17] years) met the inclusion criteria. Mean follow-up between first postoperative measurement and latest follow-up was 49 ± 22 (24-112) months. No statistical differences in PJA and DJA values were available at pre-fusion, first post-fusion, or latest follow-up (p = 0.827, p = 0.076). Fifty percent of patients had extension of TGR instrumentation at fusion, either proximal or distal. No factor including sex and etiology, lumbar lordosis, thoracic kyphosis, major curve magnitude, PJA, and DJA at pre-fusion was found to be a predictive issue for extension of index TGR instrumentation, except the history of at least one implant-related complication during the period from index surgery to the definitive fusion.

CONCLUSION

PJA and DJA remained stable when transitioning from TGR to final posterior spinal fusion. But 50% of patients had extension of construction at fusion, either proximal or distal.

摘要

目的

探讨特发性脊柱侧凸患儿经传统生长棒(TGR)转换为确定性脊柱融合术后交界区问题的风险和预测因素。

方法

回顾性分析多中心特发性脊柱侧凸数据库。纳入至少接受 2 年随访并最终行融合术的 TGR 患者。在术前、术后(手术 1 年内)和末次随访时拍摄侧位站立位脊柱全长片,测量近端交界角(PJA)和远端交界角(DJA)。统计分析指定时间点的差异和交界区问题的预测因素。

结果

251 例患者中,46 例(28 例女性,18 例男性;最终融合时的平均年龄为 12±2[9-17]岁)符合纳入标准。术后第一次测量到末次随访的平均随访时间为 49±22(24-112)个月。术前、术后第一次和末次随访时 PJA 和 DJA 值无统计学差异(p=0.827,p=0.076)。50%的患者在融合时近端或远端延长了 TGR 器械。除了在从索引手术到确定性融合的期间有至少一次与植入物相关的并发症的病史外,性别和病因、腰椎前凸度、胸椎后凸度、主曲线大小、术前 PJA 和 DJA 等因素均不能预测索引 TGR 器械的延长。

结论

从 TGR 过渡到最终后路脊柱融合时,PJA 和 DJA 保持稳定。但 50%的患者在融合时近端或远端延长了结构。

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J Korean Neurosurg Soc. 2019 Sep;62(5):577-585. doi: 10.3340/jkns.2019.0094. Epub 2019 Aug 30.
2
Upper Instrumented Vertebrae Distal to T2 Leads to a Higher Incidence of Proximal Junctional Kyphosis During Growing-rod Treatment for Early Onset Scoliosis.在早发性脊柱侧弯的生长棒治疗中,T2远端的上固定椎导致近端交界性后凸发生率更高。
Clin Spine Surg. 2018 Aug;31(7):E337-E341. doi: 10.1097/BSD.0000000000000661.
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Decision Making of Graduation in Patients With Early-Onset Scoliosis at the End of Distraction-Based Programs: Risks and Benefits of Definitive Fusion.
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Spine Deform. 2018 May-Jun;6(3):308-313. doi: 10.1016/j.jspd.2017.10.005.
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Sagittal plane parameters in growing rod patients following final fusion.
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