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尼泊尔儿童的免疫接种状况及相关因素,2016 年。

Immunization status of children in Nepal and associated factors, 2016.

机构信息

Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA.

Division of Epidemiology I, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD 20993, USA.

出版信息

Vaccine. 2021 Sep 24;39(40):5831-5838. doi: 10.1016/j.vaccine.2021.08.059. Epub 2021 Aug 26.

Abstract

BACKGROUND

Nepal has made substantial improvements in childhood immunization uptake. However, vaccination levels are still below the country-specific Sustainable Development Goal target of 94.8% coverage by 2025 for children aged 12-23 months who received all immunizations recommended in the national immunization schedule by their first birthday. A better understanding of the predictors of full immunization can inform successful programmatic interventions to improve coverage while also guiding resource allocation to ensure all children are fully vaccinated. This study estimates childhood immunization coverage in Nepal and characterizes the association between immunization status and various sociodemographic predictors.

METHODS

Data from the 2016 Nepal Demographic and Health Survey were used to examine the immunization status of children aged 12-23 months. Immunization status was categorized as fully immunized (receiving all recommended doses), under-immunized (receiving at least one, but not all, recommended doses), and un-immunized (not receiving any doses of any vaccine). Associations between full and under-immunization and potential sociodemographic predictors were assessed using logistic regression.

RESULTS

Among 976 children, 78.2% were fully immunized, 21% were under-immunized, and 0.8% were un-immunized. Retention of an immunization card was significantly associated with full immunization status. Mothers who had completed a formal education above secondary school and mothers who were working at time of interview had increased odds of full immunization. Birthing in an institutional setting was also associated with higher odds of full immunization.

CONCLUSIONS

Overall, immunization coverage in Nepal is relatively high, although it varies by dose and sociodemographic factors. Almost 25% of Nepalese children were not fully immunized, leaving them at increased risk for vaccine-preventable disease related morbidity and mortality. Nepal must continue focused efforts to reach every child and minimize the equity gap; programs may focus on advocating for the use of immunization cards, education and empowerment for girls, and delivery in institutional settings.

摘要

背景

尼泊尔在儿童免疫接种率方面取得了重大进展。然而,接种率仍低于该国 2025 年的具体可持续发展目标,即到 2025 年,所有在国家免疫计划中按年龄推荐的免疫接种都应在一岁生日前完成的 12-23 个月儿童的覆盖率达到 94.8%。更好地了解完全免疫的预测因素可以为成功的方案干预提供信息,以提高覆盖率,同时指导资源分配,确保所有儿童都完全接种疫苗。本研究估计了尼泊尔的儿童免疫接种率,并描述了免疫状况与各种社会人口预测因素之间的关联。

方法

使用 2016 年尼泊尔人口与健康调查的数据来检查 12-23 个月儿童的免疫状况。免疫状况分为完全免疫(接种所有推荐剂量)、未完全免疫(至少接种一剂,但未接种所有推荐剂量)和未免疫(未接种任何疫苗)。使用逻辑回归评估完全和未完全免疫与潜在社会人口预测因素之间的关联。

结果

在 976 名儿童中,78.2%完全免疫,21%未完全免疫,0.8%未免疫。保留免疫卡与完全免疫状况显著相关。完成中学以上正规教育的母亲和接受采访时工作的母亲具有更高的完全免疫几率。在机构环境中分娩也与更高的完全免疫几率相关。

结论

总体而言,尼泊尔的免疫接种覆盖率相对较高,尽管它因剂量和社会人口因素而异。近 25%的尼泊尔儿童未完全免疫,使他们面临更高的疫苗可预防疾病相关发病率和死亡率的风险。尼泊尔必须继续集中精力为每个儿童接种疫苗,并尽量减少公平差距;方案可以侧重于提倡使用免疫卡、为女孩提供教育和赋权,以及在机构环境中分娩。

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