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个体和社区层面因素对刚果民主共和国儿童免疫接种的影响:一项多水平分析。

Individual- and community-level determinants of child immunization in the Democratic Republic of Congo: A multilevel analysis.

机构信息

Nepal Development Society, Bharatpur, Chitwan, Nepal.

Centre for International Health, University of Bergen, Bergen, Norway.

出版信息

PLoS One. 2018 Aug 23;13(8):e0202742. doi: 10.1371/journal.pone.0202742. eCollection 2018.

Abstract

Understanding modifiable determinants of full immunization of children provide a valuable contribution to immunization programs and help reduce disease, disability, and death. This study is aimed to assess the individual and community-level determinants of full immunization coverage among children in the Democratic Republic of Congo. This study used data from the Demographic and Health Survey 2013-14 from the Democratic Republic of Congo. Data regarding total 3,366 children between 12 and 23 months of age were used in this study. Children who were immunized with one dose of BCG, three doses of polio, three doses of DPT, and a dose of measles vaccine was considered fully immunized. Descriptive statistics were calculated for the prevalence and distribution of full immunization coverage. Two-level multilevel logistic regression analysis, with individual-level (level 1) characteristics nested within community-level (level 2) characteristics, was used to assess the individual- and community-level determinants of full immunization coverage. This study found that about 45.3% [95%CI: 42.02, 48.52] of children aged 12-23 months were fully immunized in the DRC. The results confirmed immunization coverage varied and ranged between 5.8% in Mongala province to 70.6% in Nord-Kivu province. Results from multilevel analysis revealed that, four Antenatal Care (ANC) visits [AOR: 1.64; 95%CI: 1.23, 2.18], institutional delivery [AOR: 2.37; 95%CI: 1.52, 3.72], and Postnatal Care (PNC) service utilization [AOR: 1.43; 95%CI: 1.04, 1.95] were statistically significantly associated with the full immunization coverage. Similarly, children of mothers with secondary or higher education [AOR: 1.32; 95%CI: 1.00, 1.81] and from the richest wealth quintile [AOR: 1.96; 95%CI: 1.18, 3.27] had significantly higher odds of being fully immunized compared to their counterparts whose mothers were relatively poorer and less educated. Among the community-level characteristics, residents of the community with a higher rate of institutional delivery [AOR: 2.36; 95%CI: 1.59, 3.51] were found to be positively associated with the full immunization coverage. Also, the random effect result found about 35% of the variation in immunization coverage among the communities was attributed to community-level factors.The Democratic Republic of Congo has a noteworthy gap in full immunization coverage. Modifiable factors-particularly health service utilization including four ANC visits, institutional delivery, and postnatal visits-had a strong positive effect on full immunization coverage. The study underlines the importance of promoting immunization programs tailored to the poor and women with little education.

摘要

了解儿童完全免疫的可改变决定因素为免疫规划提供了有价值的贡献,并有助于减少疾病、残疾和死亡。本研究旨在评估刚果民主共和国儿童完全免疫覆盖的个体和社区层面决定因素。本研究使用了 2013-14 年刚果民主共和国人口与健康调查的数据。本研究共使用了 12 至 23 个月大的 3366 名儿童的数据。接受一剂卡介苗、三剂脊髓灰质炎、三剂白喉-破伤风-百日咳和一剂麻疹疫苗的儿童被认为是完全免疫。计算了完全免疫覆盖的流行率和分布的描述性统计数据。使用个体层面(一级)特征嵌套在社区层面(二级)特征的两水平多水平逻辑回归分析,评估完全免疫覆盖的个体和社区层面决定因素。本研究发现,12-23 个月大的儿童中约有 45.3%(95%CI:42.02,48.52)完全免疫。结果证实,免疫覆盖率存在差异,从蒙加拉省的 5.8%到北基伍省的 70.6%不等。多水平分析结果显示,四次产前护理(ANC)就诊[优势比:1.64;95%CI:1.23,2.18]、机构分娩[优势比:2.37;95%CI:1.52,3.72]和产后护理(PNC)服务利用[优势比:1.43;95%CI:1.04,1.95]与完全免疫覆盖有统计学显著关联。同样,母亲受过中等或高等教育的儿童[优势比:1.32;95%CI:1.00,1.81]和来自最富有五分之一的儿童[优势比:1.96;95%CI:1.18,3.27]与母亲相对较贫穷和教育程度较低的儿童相比,完全免疫的可能性要高得多。在社区层面特征中,产妇分娩机构比例较高的社区居民[优势比:2.36;95%CI:1.59,3.51]与完全免疫覆盖呈正相关。此外,随机效应结果发现,社区层面因素导致了免疫接种率在社区之间的 35%左右的差异。刚果民主共和国在完全免疫覆盖率方面存在显著差距。可改变的因素——特别是包括四次产前护理、机构分娩和产后护理在内的卫生服务利用——对完全免疫覆盖有积极影响。这项研究强调了针对贫困和受教育程度较低的妇女制定免疫规划的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d41/6107214/ddad145ca9bd/pone.0202742.g001.jpg

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