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[Ⅲ期(世界卫生组织)高血压患者夜间血压行为的变化——病例报告]

[Variation in nocturnal blood pressure behavior in stage III (WHO) hypertension--a case report].

作者信息

Quietzsch D, Liebert A, Kusch N, Baronius W, Büchner H, Zimmermann S

机构信息

Klinik für Innere Medizin Küchwald, Bezirkskrankenhauses Friedrich Wolf, Karl-Marx-Stadt.

出版信息

Z Gesamte Inn Med. 1987 Dec 15;42(24):707-10.

PMID:3445657
Abstract

In some cases of hypertensive men the authors obtained 24-hour blood pressure profiles by easy non-invasive technique (Mercury manometer) and under the usual atmosphere and activities of a hospital. The control Group, 32 normotensive men, showed a normal circadian blood pressure variability with systolic acrophases at 10.00 h and 16.00 h and a bathyphase around 3.00 h. The diastolic blood pressure had a smaller variability. One patient with essential hypertension stage II (WHO), case 1, kept the normal day-night rhythm. By case 2, a man with essential hypertension stage III (WHO), the authors refer to the possibility of considerable differences of blood pressure behaviour during the night in cases of severe hypertension in contrary to normal blood pressure variability. After a supplementary fourth medication this patient showed a significant decrease of blood pressure during the night. Nevertheless he kept his acrophase at night. The recording of day-night profiles of blood pressure seems to be useful in relation to the judgement of classification of severity, of the mode of anti-hypertensive medication and of the success in therapy.

摘要

在一些高血压男性患者中,作者通过简便的无创技术(水银血压计)并在医院通常的环境和日常活动状态下获取了24小时血压数据。对照组为32名血压正常的男性,其血压呈现正常的昼夜变化规律,收缩压峰值出现在10:00和16:00,低谷期在3:00左右。舒张压的变化较小。一名患有二期原发性高血压(世界卫生组织标准)的患者(病例1)保持了正常的昼夜节律。而另一名患有三期原发性高血压(世界卫生组织标准)的患者(病例2),作者指出,与正常血压变化情况相反,严重高血压患者夜间的血压行为可能存在显著差异。在追加第四种药物治疗后,该患者夜间血压显著下降。然而,其夜间血压峰值时间仍保持不变。记录血压的昼夜变化情况对于判断高血压的严重程度分级、抗高血压药物治疗方式以及治疗效果似乎是有用的。

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