Nichols Larry, Bridgewater Joshua Curtis, Wagner Nicholas Brennan
Mercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA.
Autops Case Rep. 2021 Aug 20;11:e2021314. doi: 10.4322/acr.2021.314. eCollection 2021.
Blood transfusion for chronic anemia can lead to acute or decompensated heart failure in patients who have fluid overload as part of their compensatory response and/or have intrinsic heart disease, and then it could be fatal in such clinical scenarios. This is the report of a case of profound chronic anemia in a young male patient, who was not transfused and then developed confusion followed by terminal cardiopulmonary arrest. Autopsy revealed severe trichuriasis to be the cause of the anemia, along with severe ascariasis, but minimal intrinsic brain disease. This supports the conclusion that anemia was the cause of the confusion, and the lesson that confusion may be a sign that the benefit of blood transfusion outweighs the risk in a patient with severe chronic anemia.
对于因液体超负荷作为代偿反应一部分和/或患有原发性心脏病的患者,慢性贫血输血可能导致急性或失代偿性心力衰竭,在这种临床情况下可能是致命的。本文报告一例年轻男性患者严重慢性贫血病例,该患者未接受输血,随后出现意识模糊,继而发生终末期心肺骤停。尸检显示严重鞭虫病是贫血的原因,同时伴有严重蛔虫病,但原发性脑部疾病轻微。这支持了意识模糊是由贫血引起的结论,也说明了对于严重慢性贫血患者,意识模糊可能表明输血的益处大于风险。