Gong Shiyu, Zhou Jian, Li Bingyu, Kang Sheng, Ma Xiaoye, Cai Ying, Guo Yang, Hu Rui, Zhang Xumin
Department of Cardiovascular Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Department of Cardiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Front Cardiovasc Med. 2021 Aug 12;8:677885. doi: 10.3389/fcvm.2021.677885. eCollection 2021.
The probability of late recurrent atrial fibrillation (AF) after radiofrequency ablation (RFA) has not yet been fully clarified. This study aims to study the association of left atrial appendage (LAA) morphology with AF recurrence after RFA. We retrospectively enrolled 84 patients (24 patients had persistent AF, 60 patients had paroxysmal AF) who underwent RFA in Shanghai East Hospital from June 2014 to May 2018. The mean follow-up of these patients was 618.6 days. According to preoperative transesophageal echocardiography (TEE), the morphology feature of LAA was classified and evaluated by two classification methods. The first method was divided into chicken-wing, windsock, cactus, and cauliflower, and the second method was divided into one lobe, two lobes, and multiple lobes. The correlation between morphological feature of LAA and the recurrence rate of AF after RFA was analyzed. During follow-up, 12 patients (50%) and 10 patients (16.7%) had AF recurrence in persistent and paroxysmal AF, respectively. The LAA morphology was associated with the recurrence of AF after RFA with the chicken-wing highest recurrence risk (68.2%). The structure type of LAA was also related to the AF recurrence rate ( < 0.01). Compared with one lobe and multiple lobes, two lobes (recurrence, 47.6%) were more likely associated with the recurrence of AF ( < 0.02). Logistic regression analysis showed that the chicken-wing group had a higher risk of recurrence after RFA (OR = 8.13, = 0.004), and the windsock group had a lower risk of recurrence (OR = 0.17, = 0.002). The morphological feature of LAA is related to the recurrence risk of AF after RFA. LAA morphology assessment can predict the risk of AF recurrence.
射频消融(RFA)术后晚期复发性心房颤动(AF)的概率尚未完全阐明。本研究旨在探讨左心耳(LAA)形态与RFA术后AF复发的相关性。我们回顾性纳入了2014年6月至2018年5月在上海东方医院接受RFA的84例患者(24例为持续性AF,60例为阵发性AF)。这些患者的平均随访时间为618.6天。根据术前经食管超声心动图(TEE),采用两种分类方法对LAA的形态特征进行分类和评估。第一种方法分为鸡翅型、风袋型、仙人掌型和菜花型,第二种方法分为单叶型、双叶型和多叶型。分析了LAA形态特征与RFA术后AF复发率之间的相关性。随访期间,持续性AF组有12例(50%)患者发生AF复发,阵发性AF组有10例(16.7%)患者发生AF复发。LAA形态与RFA术后AF复发相关,鸡翅型复发风险最高(68.2%)。LAA的结构类型也与AF复发率相关(<0.01)。与单叶型和多叶型相比,双叶型(复发率47.6%)更易与AF复发相关(<0.02)。Logistic回归分析显示,鸡翅型组RFA术后复发风险较高(OR = 8.13,= 0.004),风袋型组复发风险较低(OR = 0.17,= 0.002)。LAA的形态特征与RFA术后AF复发风险相关。LAA形态评估可预测AF复发风险。