Stinson Wade, Bjordahl Paul
Department of General Surgery, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Sanford Surgical Associates, Sioux Falls, South Dakota.
S D Med. 2021 Aug;74(8):376-379.
Paragangliomas are non-epithelial tumors of neuroendocrine origin that arise from the paraganglia of the sympathetic and parasympathetic nervous system. These paraganglia cells are derived from the neural crest and can be found anywhere in the body where paraganglia exist. Paragangliomas are rare tumors. It is estimated that the incidence of pheochromocytoma (intra-adrenal paraganglioma) and extra-adranal paraganglioma is 0.8 per 100,000 person years. It is commonly stated that 10 percent of paragangliomas are extra-adrenal. The majority of parasymphathetic paragangliomas reside in the skull base and along the vagus and glossopharyngeal nerves, whereas the majority of sympathetic paragangliomas can be found in the abdomen. Paragangliomas found in the mesentery are exceedingly rare, with 12 reported cases identified in the literature. We present the case of a 61-year-old female who presented to our institution with a suspected superior mesenteric artery aneurysm who was ultimately found to have an extra-adrenal paraganglioma within the small bowel mesentery of the right lower quadrant of the abdomen.
副神经节瘤是起源于神经内分泌的非上皮性肿瘤，由交感神经系统和副交感神经系统的副神经节产生。这些副神经节细胞起源于神经嵴，存在于体内有副神经节的任何部位。副神经节瘤是罕见肿瘤。据估计，嗜铬细胞瘤（肾上腺内副神经节瘤）和肾上腺外副神经节瘤的发病率为每10万人年0.8例。通常认为10%的副神经节瘤位于肾上腺外。大多数副交感神经节瘤位于颅底以及迷走神经和舌咽神经沿线，而大多数交感神经节瘤位于腹部。肠系膜中发现的副神经节瘤极为罕见，文献中仅报道了12例。我们报告了一例61岁女性病例，该患者因疑似肠系膜上动脉动脉瘤前来我院就诊，最终发现其右下腹小肠系膜内有一个肾上腺外副神经节瘤。
