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精神疾病患者的口腔疾病患病率:伞式综述。

Prevalence of dental disorders among people with mental illness: An umbrella review.

机构信息

Jisu Choi - Faculty of Science, Dan Siskind & Steve Kisely - Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.

Princess Alexandra Hospital Southside Clinical Unit, Metro South Health Service, Woolloongabba, QLD, Australia.

出版信息

Aust N Z J Psychiatry. 2022 Aug;56(8):949-963. doi: 10.1177/00048674211042239. Epub 2021 Aug 30.

Abstract

OBJECTIVE

Psychiatric patients have increased rates of comorbid physical illness. There are less data on dental disease, especially decay, despite risk factors including lifestyle and psychotropic side effects such as xerostomia. We therefore undertook an umbrella review of all meta-analyses on the association between mental illness and oral health.

METHODS

We searched PubMed, MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, Embase and CINAHL. Articles were independently assessed. Outcomes were caries, periodontal disease, erosion, and partial or total tooth loss (edentulism), measured where possible with standardised measures such as the mean number of decayed, missing and filled teeth or surfaces. Quality was assessed in line with National Institutes of Health guidelines.

RESULTS

We identified 11 meta-analyses. The most information and strongest association was between dental decay and severe mental illness or substance use, as well as erosion and eating disorders. Depressive, anxiety and eating disorders were also associated with caries, but the datasets were small. People with severe mental illness had nearly three times the odds of having lost all their teeth than the general community (odds ratio = 2.81, 95% confidence interval = [1.73, 4.57]) and those with depression between 1.17 and 1.32. Findings for periodontal disease were more equivocal, possibly because of study heterogeneity.

CONCLUSION

Mental health clinicians should screen for oral diseases when treating those with mental illness and facilitate referral to affordable dental clinics when indicated. Prevention should be a priority, including the promotion of dental care, as well as the management of xerostomia when psychopharmacologic agents are prescribed.

摘要

目的

精神疾病患者合并躯体疾病的比例较高。尽管存在生活方式和精神类药物副作用(如口干)等风险因素,但有关牙科疾病(尤其是龋齿)的资料却较少。因此,我们对所有关于精神疾病与口腔健康相关性的荟萃分析进行了伞式综述。

方法

我们检索了 PubMed、MEDLINE、PsycINFO、Cochrane 对照试验中心注册库、Embase 和 CINAHL。文章由独立评估。如果可能,使用龋齿、牙周病、侵蚀和部分或全部牙齿缺失(无牙)等标准化指标来衡量龋齿、牙周病、侵蚀和部分或全部牙齿缺失(无牙)等结局。根据美国国立卫生研究院的指南评估质量。

结果

我们确定了 11 项荟萃分析。信息最多、相关性最强的是严重精神疾病或物质使用与龋齿、侵蚀和饮食失调的关系。抑郁、焦虑和饮食失调也与龋齿有关,但数据集较小。严重精神疾病患者失去所有牙齿的可能性是普通人群的近三倍(优势比 = 2.81,95%置信区间 = [1.73, 4.57]),而患有抑郁症的患者则为 1.17 至 1.32。牙周病的发现则更加不确定,可能是由于研究异质性。

结论

精神健康临床医生在治疗精神疾病患者时应筛查口腔疾病,并在需要时为其提供负担得起的牙科诊所转介服务。预防应成为优先事项,包括促进口腔保健,以及在开具精神药理学药物时管理口干。

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