Abdali A, Astafeva L I, Trunin Yu Yu, Chernov I V, Sidneva Yu G, Abdilatipov A A, Kalinin P L
Peoples' Friendship University of Russia, Moscow, Russia.
Burdenko Neurosurgical Center, Moscow, Russia.
Zh Vopr Neirokhir Im N N Burdenko. 2021;85(4):111-117. doi: 10.17116/neiro202185041111.
Cushing's disease is a severe neuroendocrine disorder caused by chronic hypersecretion of ACTH by pituitary adenoma (corticotropinoma). Surgical resection is a gold standard for this disease resulting stable remission in about 65-95% of cases. Despite benign nature of corticotropinoma, recurrence rate is still higher (25-35%) even in specialized neurosurgical centers. Modifications in surgical strategy can prolong recurrence-free period.
库欣病是一种严重的神经内分泌疾病，由垂体腺瘤（促肾上腺皮质激素瘤）慢性过度分泌促肾上腺皮质激素（ACTH）引起。手术切除是这种疾病的金标准，约65% - 95%的病例可实现病情稳定缓解。尽管促肾上腺皮质激素瘤本质上是良性的，但即使在专业的神经外科中心，复发率仍然较高（25% - 35%）。手术策略的调整可以延长无复发期。
