经支气管镜结核空洞封堵治疗肺结核。
Transbronchial tuberculosis cavity plugging therapy for pulmonary tuberculosis.
机构信息
Tuberculosis Department, TCM Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Haihe Hospital, Tianjin, China.
Respiratory Department, TCM Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin Haihe Hospital, Tianjin, China.
出版信息
J Int Med Res. 2021 Aug;49(8):3000605211035889. doi: 10.1177/03000605211035889.
OBJECTIVE
To investigate the effect of drug treatment combined with interventional cavity therapy for cavitary pulmonary tuberculosis.
METHODS
One-hundred thirty patients who underwent transbronchial tuberculosis cavity plugging (TTCP) combined with drug therapy from 2012 to 2018 were selected as the observation group, and 130 patients with cavitary tuberculosis who underwent treatment with drugs only were selected as the control group. Changes in cavity size and sputum tests were compared between the two groups. In addition, adverse reactions were monitored.
RESULTS
The number of cases with cavity closure was significantly higher in the observation group than in the control group at different time points. The number and proportion of negative sputum samples in the observation group were significantly higher than those in the control group. The treatment success rate was 98.46% in the observation group and 92.3% in the control group. No recurrence was observed in the observation group, and 8.3% of cases in the control group showed recurrence.
CONCLUSIONS
TTCP for the treatment of cavity tuberculosis showed good outcomes, with limited side effects and minimal complications.
目的
探讨药物治疗联合介入性空洞疗法治疗空洞性肺结核的效果。
方法
选取 2012 年至 2018 年期间行支气管镜结核空洞封堵术（TTCP）联合药物治疗的 130 例空洞性肺结核患者作为观察组，选取同期单纯药物治疗的 130 例空洞性肺结核患者作为对照组。比较两组患者空洞大小和痰检变化情况，同时监测不良反应。
结果
观察组不同时间点的空洞闭合例数明显多于对照组，观察组的阴转例数和阴转率明显高于对照组。观察组的治疗成功率为 98.46%，对照组为 92.3%。观察组无复发，对照组有 8.3%的病例复发。
结论
TTCP 治疗空洞性肺结核效果良好，副作用有限，并发症少。
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