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溶血:机制及临床生物学后果。

Hemolysis: Mechanism and clinico-biological consequences.

机构信息

Département de médecine, hôpitaux universitaires de Genève, 4, rue Gabrielle Perret-Gentil, 1211 Genève, Switzerland.

出版信息

Transfus Clin Biol. 2021 Nov;28(4):364-366. doi: 10.1016/j.tracli.2021.08.352. Epub 2021 Aug 28.

DOI:10.1016/j.tracli.2021.08.352
PMID:34464714
Abstract

Hemolysis is a clinical entity, which can be severe. It is commonly of multifactorial etiology. The activity of a specialist in transfusion medicine consists in treating the patient with transfusion support in case of severe anemia. If the etiology is partly alloimmune this therapeutic strategy is more arduous. Immunohematological work-up must be very rigorous to ensure transfusion management with utmost safety. However, without the precise knowledge of both the clinical condition and the treatment (current and past) of the patient, such management is impossible.

摘要

溶血是一种临床病症,可能很严重。它通常是多因素病因。输血医学专家的工作是在严重贫血的情况下用输血支持来治疗患者。如果病因部分是同种免疫性的,这种治疗策略就更加困难。免疫血液学检查必须非常严格,以确保输血管理的最大安全性。然而,如果没有对患者的临床状况和治疗(现在和过去)的准确了解,这种管理是不可能的。

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1
Hemolysis: Mechanism and clinico-biological consequences.溶血:机制及临床生物学后果。
Transfus Clin Biol. 2021 Nov;28(4):364-366. doi: 10.1016/j.tracli.2021.08.352. Epub 2021 Aug 28.
2
Type-specific cold auto-antibodies as a cause of acquired hemolytic anemia and hemolytic transfusion reactions: biologic test with bovine red cells.特定血型的冷凝集素作为获得性溶血性贫血和溶血性输血反应的病因:用牛红细胞进行生物学检测
Ann Intern Med. 1956 Feb;44(2):221-40. doi: 10.7326/0003-4819-44-2-221.
3
A FATAL HEMOLYTIC TRANSFUSION REACTION WITH ACUTE AUTOHEMOLYSIS.一例伴有急性自身溶血的致命性溶血性输血反应
Transfusion. 1964 Jul-Aug;4:285-92. doi: 10.1111/j.1537-2995.1964.tb02874.x.
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Drug-induced hemolysis: cefotetan-dependent hemolytic anemia mimicking an acute intravascular immune transfusion reaction.药物性溶血:头孢替坦依赖性溶血性贫血酷似急性血管内免疫性输血反应。
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[Transfusion of patients with autoimmune hemolytic anemia].[自身免疫性溶血性贫血患者的输血]
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Prolonged in vitro hemolysis of EDTA-anticoagulated blood after a delayed hemolytic transfusion reaction.延迟性溶血性输血反应后,乙二胺四乙酸(EDTA)抗凝血液在体外发生长时间溶血。
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Acute hemolytic reaction due to A-B mismatched transfusion in a cat with transient AB blood type.一只具有短暂AB血型的猫因A-B血型不匹配输血导致急性溶血反应。
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Rare antibody-associated hemolytic transfusion reaction and transfusion-related acute lung injury: a case report.罕见的抗体相关溶血性输血反应及输血相关急性肺损伤:一例报告
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[Treatment of hemolytic shock and anuria following transfusion of incompatible blood].[输血不相容后溶血性休克和无尿的治疗]
Vestn Khir Im I I Grek. 1956 May;77(5):77-9.

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