Department of Ophthalmology, Philipps University of Marburg, Marburg, Germany.
Cornea. 2022 Jul 1;41(7):826-832. doi: 10.1097/ICO.0000000000002833. Epub 2021 Aug 30.
To evaluate the short- and mid-term changes of corneal thickness spatial profile (CTSP), corneal volume distribution (CVD), and corneal asphericity after small-incision lenticule extraction (SMILE) for correction of myopia and astigmatism and compare the results with femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK).
Thirty eyes of 18 patients who underwent SMILE were compared with a group of 30 eyes of 16 patients who underwent FS-LASIK. The groups were matched for preoperative central corneal thickness and lenticule thickness/ablation depth. Scheimpflug corneal tomography was performed preoperatively and postoperatively at 2 months and 3 years. The CTSP was evaluated on 4 concentric rings (2, 4, 6, and 8 mm). The CVD was evaluated at 3 concentric zones (3, 5, and 7 mm). Changes in the anterior and posterior asphericity at a 6-mm zone were also evaluated.
Between the 2-month and 3-year examination, the CTSP showed a similar increase for both groups at all measured points and rings ( P ≥ 0.168). The CVD also showed a similar increase for both groups at all measured zones ( P ≥ 0.278). The anterior corneal asphericity remained stable after SMILE (2-mo Q = 0.46 ± 0.27; 3-yr Q = 0.45 ± 0.27; P = 0.711) but decreased significantly after FS-LASIK (2-mo Q = 0.52 ± 0.47; 3-yr Q = 0.47 ± 0.44; P = 0.028). Similarly, the posterior corneal asphericity remained stable after SMILE (2-mo Q = -0.11 ± 0.15; 3-yr Q = -0.11 ± 0.13; P = 0.902) but decreased significantly after FS-LASIK (2-mo Q = -0.13 ± 0.14; 3-yr Q = -0.16 ± 0.15; P = 0.034).
CTSP and CVD between the 2-month and 3-year examination showed a similar increase after SMILE and FS-LASIK. During the postoperative course, the anterior and posterior corneal asphericity remained more stable after SMILE compared with FS-LASIK.
评估小切口微透镜提取术（SMILE）矫正近视和散光后角膜厚度空间分布（CTSP）、角膜体积分布（CVD）和角膜非球面性的短期和中期变化，并与飞秒激光辅助原位角膜磨镶术（FS-LASIK）进行比较。
将 18 例患者的 30 只眼与 16 例患者的 30 只眼进行比较，这些患者在术前中央角膜厚度和微透镜厚度/消融深度方面相匹配。术前和术后 2 个月和 3 年均进行 Scheimpflug 角膜断层扫描。在 4 个同心环（2、4、6 和 8mm）上评估 CTSP。在 3 个同心区域（3、5 和 7mm）评估 CVD。还评估了 6mm 区域前后表面非球面性的变化。
在 2 个月至 3 年的检查中，两组在所有测量点和环上的 CTSP 均显示出相似的增加（P≥0.168）。两组在所有测量区域的 CVD 也显示出相似的增加（P≥0.278）。SMILE 后前角膜非球面性保持稳定（2 个月 Q=0.46±0.27；3 年 Q=0.45±0.27；P=0.711），但 FS-LASIK 后明显降低（2 个月 Q=0.52±0.47；3 年 Q=0.47±0.44；P=0.028）。同样，SMILE 后后角膜非球面性保持稳定（2 个月 Q=-0.11±0.15；3 年 Q=-0.11±0.13；P=0.902），但 FS-LASIK 后明显降低（2 个月 Q=-0.13±0.14；3 年 Q=-0.16±0.15；P=0.034）。
SMILE 和 FS-LASIK 后 2 个月至 3 年的 CTSP 和 CVD 检查均显示出相似的增加。在术后过程中，SMILE 后前、后角膜非球面性较 FS-LASIK 更稳定。
