Department of Sensors and Biomedical Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, OH, USA.
J Ultrasound. 2022 Sep;25(3):469-474. doi: 10.1007/s40477-021-00606-7. Epub 2021 Sep 1.
The aim of this study is to investigate the changes in median nerve and transverse carpal ligament (TCL)-formed carpal arch morphology as possible risk factors for median nerve entrapment in women with type 2 diabetes.
The distal carpal tunnel was imaged using ultrasound in 30 female subjects (15 with type 2 diabetes, 15 controls). The morphological parameters of the median nerve and carpal arch were derived from the ultrasound images. One-way analysis of variance (ANOVA) was used for statistical analysis.
Diabetic women had an enlarged median nerve area (p < 0.05), salong with a maller carpal arch size, as indicated by a reduced palmar bowing index of the TCL (p < 0.05), and arch area (p < 0.05) than controls. The distance from the median nerve centroid to the volar boundary of the TCL was reduced in diabetic women (p < 0.05) compared to the controls.
Women with type 2 diabetes have reduced available space for the median nerve within the carpal arch due to the enlarged nerve and reduced arch size, making the median nerve more susceptible to entrapment within the tunnel. The current study shows that presence of diabetes increases the risk of median nerve entrapment in women and requires early detection of symptoms to avoid carpal tunnel syndrome.
本研究旨在探讨 2 型糖尿病女性正中神经和横腕韧带（TCL）形成的腕弓形态变化是否为正中神经受压的可能危险因素。
使用超声对 30 名女性受试者（15 名 2 型糖尿病患者，15 名对照）的远端腕管进行成像。从超声图像中得出正中神经和腕弓的形态参数。采用单因素方差分析（ANOVA）进行统计分析。
与对照组相比，糖尿病女性的正中神经面积增大（p<0.05），TCL 的掌弓指数减小（p<0.05），弓面积减小（p<0.05），表明腕弓尺寸较小。与对照组相比，糖尿病女性正中神经中心到 TCL 掌侧边界的距离减小（p<0.05）。
由于神经增大和弓尺寸减小，2 型糖尿病女性腕管内正中神经的可用空间减小，使正中神经更容易在隧道内受压。本研究表明，糖尿病的存在增加了女性正中神经受压的风险，需要早期发现症状以避免腕管综合征。
