School of Materials Science and Engineering, Zhengzhou University, Zhengzhou, China.
School of Physical Science and Technology, ShanghaiTech University, Shanghai, China.
Methods Mol Biol. 2021;2347:27-33. doi: 10.1007/978-1-0716-1574-4_3.
As the extracellular matrix protein, elastin is a crucial component of connective tissue in life. It is responsible for the structural integrity and function of tissues undergoing reversible extensibility or deformability, even though it may make up only a small percentage of a tissue. The structure stability, elastic resilience, bioactivity, and ability of self-assembly make elastin a highly desirable candidate for the fabrication of biomaterials. Elastin's properties mainly depend on their special structure. As elastin can be obtained by the assembly and cross-linking of its soluble precursor, tropoelastin. This chapter centers on introducing the structure of those two materials.
作为细胞外基质蛋白，弹性蛋白是生命中结缔组织的关键组成部分。它负责具有可伸缩性或可变形性的组织的结构完整性和功能，即使它可能只占组织的一小部分。结构稳定性、弹性回弹性、生物活性和自组装能力使弹性蛋白成为制造生物材料的理想候选材料。弹性蛋白的性质主要取决于其特殊的结构。由于弹性蛋白可以通过其可溶性前体原弹性蛋白的组装和交联获得。本章主要介绍这两种材料的结构。
