Zunyi Medical University, Zunyi, Guizhou, China.
Department of Cardiothoracic Surgery, Chengdu Second People's Hospital, Chengdu, Sichuan, China.
Heart Surg Forum. 2021 Aug 25;24(4):E746-E750. doi: 10.1532/hsf.3977.
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease, and its main characteristic is symmetrical or asymmetrical hypertrophy of the left ventricle and/or right ventricle. Most previous studies mainly include the left ventricle for definition of HCM, thus neglecting the right ventricle. But recently, many studies have reported the right ventricular involvement in HCM. Histopathological results showed that similar pathogenic changes in both the right and left ventricles, which suggests common myopathic processes and sarcomere genetic mutations. Cardiovascular magnetic resonance (CMR) is a gold standard imaging modality to assess heart anatomy and function and provides highly accurate and reproducible measurements. CMR is very useful in characterizing the various phenotypes of right and left ventricles in HCM. CMR also can be useful in detecting early and dominant phenotypic expression of HCM. Due to the complex geometry of the right ventricle and its retrosternal position, echocardiography may not provide accurate measurements. CMR also provides more accurate and repeatable right ventricular measurements. Thus, right ventricle evaluation along with left ventricle should routinely be done for better assessment of HCM patients.
肥厚型心肌病（HCM）是最常见的遗传性心脏病，其主要特征为左心室和/或右心室呈对称性或非对称性肥厚。大多数先前的研究主要包括左心室来定义 HCM，从而忽略了右心室。但最近，许多研究报告了 HCM 中的右心室受累。组织病理学结果表明，左右心室存在相似的致病变化，这提示存在共同的肌病过程和肌节基因突变。心血管磁共振（CMR）是评估心脏解剖和功能的金标准成像方式，提供高度准确和可重复的测量。CMR 对于表征 HCM 中左右心室的各种表型非常有用。CMR 还可用于检测 HCM 的早期和主要表型表达。由于右心室的复杂几何形状及其胸骨后位置，超声心动图可能无法提供准确的测量。CMR 还可提供更准确和可重复的右心室测量。因此，为了更好地评估 HCM 患者，应常规进行右心室评估以及左心室评估。
