Lv Xin, Han Taihe, Wu Yi, Zhang Boran, Guo Wei
School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
Chem Commun (Camb). 2021 Sep 23;57(76):9744-9747. doi: 10.1039/d1cc03360c.
A new class of NIR distyryl Bodipy fluorescent dyes were developed with sulfone- and quaternary ammonium-modified piperidines as auxochromes instead of conventional dialkylamino auxochromes. Such modification markedly improved the fluorescence quantum yields due to the efficient inhibition of the twisted intramolecular charge transfer (TICT) state. Based on the dye platform, we developed a new fluorescent HO probe self-immolative chemistry, and confirmed its capability to sensitively and selectively sense HO and .
开发了一类新型的近红外二苯乙烯基硼二吡咯荧光染料，用砜和季铵修饰的哌啶作为助色团，取代了传统的二烷基氨基助色团。由于有效抑制了扭曲的分子内电荷转移（TICT）态，这种修饰显著提高了荧光量子产率。基于该染料平台，我们利用自牺牲化学开发了一种新型荧光HO探针，并证实了其灵敏且选择性地检测HO和的能力。
