Starr Michelle C, Chaudhry Paulomi, Brock Allyson, Vincent Katherine, Twombley Katherine, Bonachea Elizabeth M, Mohamed Tahagod H
Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, IN, USA.
Medical University of South Carolina, Charleston, SC, USA.
J Perinatol. 2022 Feb;42(2):243-246. doi: 10.1038/s41372-021-01198-0. Epub 2021 Sep 3.
To describe three different standardized approaches to improving neonatal acute kidney injury (AKI) identification and the impact on AKI identification, incidence, and nephrology consultation and referral.
A retrospective cohort study in three academic NICUs. We compared AKI identification, AKI incidence, nephrology consultation, and nephrology follow-up before and after implantation of local protocols to standardize neonatal AKI identification.
Neonatal AKI identification improved in all three NICUs following protocol implementation (26-85%, P < 0.0001). Each center also saw increases in nephrology consultation (15-83%, P < 0.0001) and nephrology follow-up (7-73%, P < 0.0001). AKI incidence decreased significantly (21-12%, P < 0.0001).
Multiple strategies can be successfully operationalized to improve neonatal AKI identification. While different in approach, each strategy resulted in increased AKI identification and nephrology involvement. This study emphasizes the importance of local standardized approaches to AKI to improve AKI identification and nephrology involvement in the NICU.
描述三种不同的标准化方法,以改善新生儿急性肾损伤(AKI)的识别,以及这些方法对AKI识别、发病率、肾病会诊和转诊的影响。
在三个学术性新生儿重症监护病房(NICU)进行的一项回顾性队列研究。我们比较了在实施当地标准化新生儿AKI识别方案前后的AKI识别情况、AKI发病率、肾病会诊及肾病随访情况。
实施方案后,所有三个NICU的新生儿AKI识别情况均有所改善(提高了26%-85%,P<0.0001)。每个中心的肾病会诊(提高了15%-83%,P<0.0001)和肾病随访(提高了7%-73%,P<0.0001)也都有所增加。AKI发病率显著下降(从21%降至12%,P<0.0001)。
多种策略可成功实施以改善新生儿AKI的识别。虽然方法不同,但每种策略都导致AKI识别率提高和肾病科参与度增加。本研究强调了采用当地标准化的AKI方法对于改善NICU中AKI识别和肾病科参与度的重要性。