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[缺血再灌注综合征]

[Ischemia-reperfusion syndrome].

作者信息

Neimark M I

机构信息

Altai State Medical University, Barnaul, Russia.

出版信息

Khirurgiia (Mosk). 2021(9):71-76. doi: 10.17116/hirurgia202109171.

DOI:10.17116/hirurgia202109171
PMID:34480458
Abstract

The ischemia-reperfusion syndrome complicates the course of a number of emergency conditions in various fields of clinical medicine, determines the course, prognosis and outcome of the disease. This review examines various aspects of the etiology, pathogenesis, and clinical manifestations of this syndrome. Particular attention is paid to its prevention and treatment. It is indicated that most of the studies devoted to this problem are of an experimental nature. The use of preparations based on succinic acid in the clinic is seen as the most promising direction in solving this issue.

摘要

缺血再灌注综合征使临床医学各领域的多种急症病情复杂化,决定疾病的病程、预后和结局。本综述探讨了该综合征病因、发病机制和临床表现的各个方面。特别关注其预防和治疗。指出针对这一问题的大多数研究具有实验性质。临床上使用基于琥珀酸的制剂被视为解决这一问题最有前景的方向。

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引用本文的文献

1
Therapeutic Targets for Regulating Oxidative Damage Induced by Ischemia-Reperfusion Injury: A Study from a Pharmacological Perspective.调控缺血再灌注损伤诱导的氧化损伤的治疗靶点:药理学视角的研究。
Oxid Med Cell Longev. 2022 Apr 11;2022:8624318. doi: 10.1155/2022/8624318. eCollection 2022.
2
A narrative review of long noncoding RNA: insight into neural ischemia/reperfusion mediated by two pathophysiological processes of injury and repair.长链非编码RNA的叙述性综述:深入了解由损伤和修复两个病理生理过程介导的神经缺血/再灌注
Ann Transl Med. 2022 Feb;10(4):235. doi: 10.21037/atm-22-268.