Department of Sociology and Institute of Behavioral Science, University of Colorado Boulder, Boulder, CO, USA.
Soc Sci Med. 2021 Oct;287:114227. doi: 10.1016/j.socscimed.2021.114227. Epub 2021 Jul 14.
The HPV vaccine's effectiveness in protecting against the human papillomavirus (HPV) is dependent on both the timing of vaccine initiation (by age 12) and number of vaccine doses. This study used an intersectional approach to examine how gender and its intersection with race/ethnicity predict age-specific probabilities of initiating HPV vaccinations for boys/men and girls/women across four racial/ethnic groups: non-Latinx (NL) white, NL-Black, Latinx, and NL-Asian American. Multinomial logistic regression models-with on-time vaccination as the base outcome-examined the timing of initiating HPV vaccinations (never or late) in the 2011-2016 National Health and Nutrition Examination Survey (NHANES). This study finds that the multiplicative interaction term between gender and race/ethnicity produces significant results in the likelihood of initiating HPV vaccine uptake: NL-Asian American boys/men have the highest risk of not vaccinating on time. This finding would have been hidden with a one-dimensional analysis.
HPV 疫苗预防人乳头瘤病毒(HPV)的有效性取决于疫苗接种时间(12 岁之前)和疫苗剂量数。本研究采用交叉方法,检验了性别及其与种族/族裔的交叉如何预测四个种族/族裔群体(非拉丁裔白人、非拉丁裔黑人、拉丁裔和非拉丁裔亚裔美国人)中男孩/男性和女孩/女性的 HPV 疫苗接种年龄特异性概率。多变量逻辑回归模型——以按时接种为基础结果——检验了 2011-2016 年全国健康和营养检查调查(NHANES)中 HPV 疫苗接种的起始时间(从未接种或延迟接种)。本研究发现,性别和种族/族裔之间的乘法交互项在 HPV 疫苗接种率方面产生了显著结果:非拉丁裔亚裔美国男孩/男性及时接种疫苗的风险最高。如果采用一维分析,这一发现可能会被掩盖。