• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

少肌症的药物治疗

Pharmacological Treatment of Sarcopenia.

作者信息

Souza Caio Gonçalves de

机构信息

Grupo de Doenças Osteometabólicas, Instituto de Ortopedia e Traumatologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), Sçao Paulo, SP, Brasil.

出版信息

Rev Bras Ortop (Sao Paulo). 2021 Aug;56(4):425-431. doi: 10.1055/s-0040-1709732. Epub 2020 Sep 22.

DOI:10.1055/s-0040-1709732
PMID:34483384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8405270/
Abstract

Sarcopenia has been acquiring a growing importance in the scientific literature and in doctors' offices. As the population ages, it becomes increasingly essential to know, prevent, and treat this clinical condition. The purpose of the present review is to bring up the current evidence on the diagnosis of this pathology, in a practical way, as well as the main current treatment options.

摘要

肌肉减少症在科学文献和医生办公室中日益受到重视。随着人口老龄化,了解、预防和治疗这种临床病症变得越来越重要。本综述的目的是以实用的方式介绍有关这种病理诊断的当前证据以及当前的主要治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8df/8405270/0e6228514ebd/10-1055-s-0040-1709732-i1900193pt-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8df/8405270/fb29411dcd27/10-1055-s-0040-1709732-i1900193en-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8df/8405270/0e6228514ebd/10-1055-s-0040-1709732-i1900193pt-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8df/8405270/fb29411dcd27/10-1055-s-0040-1709732-i1900193en-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8df/8405270/0e6228514ebd/10-1055-s-0040-1709732-i1900193pt-1.jpg

相似文献

1
Pharmacological Treatment of Sarcopenia.少肌症的药物治疗
Rev Bras Ortop (Sao Paulo). 2021 Aug;56(4):425-431. doi: 10.1055/s-0040-1709732. Epub 2020 Sep 22.
2
Treating sarcopenia in clinical practice: where are we now?临床实践中治疗肌肉减少症:我们目前处于什么阶段?
Acta Clin Belg. 2016 Aug;71(4):197-205. doi: 10.1080/17843286.2016.1168064. Epub 2016 Apr 26.
3
Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people: an umbrella review of systematic reviews and meta-analyses.营养干预措施对改善老年人肌肉量、肌肉力量和身体机能的效果:系统评价和荟萃分析的伞状综述。
Nutr Rev. 2021 Jan 9;79(2):121-147. doi: 10.1093/nutrit/nuaa011.
4
Sex hormones and sarcopenia in older persons.性激素与老年人肌肉减少症。
Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):3-13. doi: 10.1097/MCO.0b013e32835b6044.
5
Interventions against sarcopenia in older persons.针对老年人肌肉减少症的干预措施。
Curr Pharm Des. 2014;20(38):5983-6006. doi: 10.2174/1381612820666140316132246.
6
17β-Estradiol and testosterone in sarcopenia: Role of satellite cells.17β-雌二醇和睾酮在肌肉减少症中的作用:卫星细胞的角色
Ageing Res Rev. 2015 Nov;24(Pt B):166-77. doi: 10.1016/j.arr.2015.07.011. Epub 2015 Aug 3.
7
Sarcopenia.肌肉减少症
Wien Med Wochenschr. 2019 May;169(7-8):157-172. doi: 10.1007/s10354-018-0618-2. Epub 2018 Feb 6.
8
Pharmacological Interventions to Improve Muscle Mass, Muscle Strength and Physical Performance in Older People: An Umbrella Review of Systematic Reviews and Meta-analyses.改善老年人肌肉量、肌肉力量和身体机能的药物干预措施:系统评价和荟萃分析的伞状综述
Drugs Aging. 2018 Aug;35(8):719-734. doi: 10.1007/s40266-018-0566-y.
9
Nutrition for Sarcopenia.肌肉减少症的营养
J Clin Med Res. 2015 Dec;7(12):926-31. doi: 10.14740/jocmr2361w. Epub 2015 Oct 23.
10
Sarcopenia and Androgens: A Link between Pathology and Treatment.肌肉减少症与雄激素:病理学与治疗之间的联系
Front Endocrinol (Lausanne). 2014 Dec 18;5:217. doi: 10.3389/fendo.2014.00217. eCollection 2014.

引用本文的文献

1
Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice.依地骨化醇通过抑制去势小鼠的PI3K/AKT/FOXOs信号通路来预防肌肉流失。
Front Pharmacol. 2022 Oct 28;13:1018480. doi: 10.3389/fphar.2022.1018480. eCollection 2022.

本文引用的文献

1
Sarcopenia: revised European consensus on definition and diagnosis.肌少症:定义和诊断的欧洲共识修订版。
Age Ageing. 2019 Jan 1;48(1):16-31. doi: 10.1093/ageing/afy169.
2
Associations of Sarcopenia Definitions, and Their Components, With the Incidence of Recurrent Falling and Fractures: The Longitudinal Aging Study Amsterdam.肌肉减少症定义及其组成部分与复发性跌倒和骨折发生率的关系:阿姆斯特丹纵向老龄化研究。
J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1199-1204. doi: 10.1093/gerona/glx245.
3
Clinical Definitions of Sarcopenia and Risk of Hospitalization in Community-Dwelling Older Men: The Osteoporotic Fractures in Men Study.
社区居住老年男性肌肉减少症的临床定义及住院风险:男性骨质疏松性骨折研究
J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1383-1389. doi: 10.1093/gerona/glw327.
4
Enhancing SARC-F: Improving Sarcopenia Screening in the Clinical Practice.增强SARC-F:改善临床实践中的肌肉减少症筛查
J Am Med Dir Assoc. 2016 Dec 1;17(12):1136-1141. doi: 10.1016/j.jamda.2016.08.004. Epub 2016 Sep 17.
5
Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS).老年人肌少症的患病率及干预措施:一项系统评价。国际肌少症倡议组织(EWGSOP和IWGS)报告
Age Ageing. 2014 Nov;43(6):748-59. doi: 10.1093/ageing/afu115. Epub 2014 Sep 21.
6
Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men.蛋白质摄入以刺激肌原纤维蛋白合成,健康老年人比年轻人需要相对更高的蛋白质摄入量。
J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):57-62. doi: 10.1093/gerona/glu103. Epub 2014 Jul 23.
7
Creatine supplementation during resistance training in older adults-a meta-analysis.老年人抗阻训练期间补充肌酸——一项荟萃分析
Med Sci Sports Exerc. 2014 Jun;46(6):1194-203. doi: 10.1249/MSS.0000000000000220.
8
Muscle mass index as a predictor of longevity in older adults.肌肉质量指数作为老年人长寿的预测指标。
Am J Med. 2014 Jun;127(6):547-53. doi: 10.1016/j.amjmed.2014.02.007. Epub 2014 Feb 18.
9
Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial.低蛋白混合宏量营养素饮料补充亮氨酸可增强年轻男性的肌原纤维蛋白合成:一项双盲、随机试验。
Am J Clin Nutr. 2014 Feb;99(2):276-86. doi: 10.3945/ajcn.113.068775. Epub 2013 Nov 27.
10
Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise.在休息时和抗阻运动后,摄入不同剂量乳清蛋白后,餐后肌原纤维肌蛋白合成速率的变化。
Am J Clin Nutr. 2014 Jan;99(1):86-95. doi: 10.3945/ajcn.112.055517. Epub 2013 Nov 20.