Basutkar Roopa Satyanarayan, Sagadevan Shonitha, Sri Hari Oorvashree, Sirajudeen Mohamed Jahangir, Ramalingam Gopi, Gobinath Pavithra, Rajesh Neha, Sivasankaran Ponnusankar
Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, The Nilgiris, Tamil Nadu 643001 India.
Government Medical College and Hospital, Ooty, The Nilgiris, Tamil Nadu 643001 India.
J Obstet Gynaecol India. 2021 Aug;71(Suppl 1):28-35. doi: 10.1007/s13224-021-01544-4. Epub 2021 Sep 1.
COVID-19 pandemic has affected the pregnant women both physically and mentally. This study is conducted to assess, the impact on COVID-19 pandemic on psychiatric symptoms among pregnancy and to compare them with non-pregnant women.
An observational study was conducted at Govt. Medical College & Hospital, Ooty (Udhagamandalam). A validated Edinburgh Depression Scale was used to screen the mental health status. Categorical variables were analysed using Chi-square test and continuous variables by independent test. A Pearson's correlation analysis was performed to check the association of Edinburgh postnatal depression scores with the demographic characteristics. Paired test was conducted to find the difference in EPDS scores at baseline and study conclusion visit. Regression analysis was conducted to predict the outcome variables.
The Edinburgh Depression scores were significantly higher in the pregnant women group, (12.48 ± 3.753 vs. 8.00 ± 2.436; value = 0.001; 95% CI 3.340-5.627), when compared to non-pregnant women (12.90 ± 3.731 vs. 9.20 ± 2.973; value = 0.001; 95% CI 2.480-4.920). The Edinburgh Depression scores at the study conclusion visit was statistically significant, (11.05 ± 3.839 vs. 10.24 ± 3.872; value = 0.008; 95% CI -1.40 to -0.213). Education, income, duration of marriage, body mass index, and suicidal ideation are some of the predictors identified in this study to cause depression among pregnant women.
The findings of the study indicate a clinically significant increase of depressive symptoms among pregnant women. It is recommended to include routine psychological screenings and interventions during pregnancy.
新冠疫情对孕妇的身心健康均产生了影响。本研究旨在评估新冠疫情对孕期精神症状的影响，并将其与非孕妇进行比较。
在乌塔卡蒙德政府医学院及医院进行了一项观察性研究。采用经过验证的爱丁堡产后抑郁量表来筛查心理健康状况。分类变量采用卡方检验进行分析，连续变量采用独立样本检验。进行Pearson相关性分析以检验爱丁堡产后抑郁评分与人口统计学特征之间的关联。采用配对样本检验来找出基线和研究结束访视时爱丁堡产后抑郁量表（EPDS）评分的差异。进行回归分析以预测结果变量。
与非孕妇相比，孕妇组的爱丁堡产后抑郁评分显著更高（12.48±3.753对8.00±2.436；t值=0.001；95%置信区间3.340 - 5.627）（12.90±3.731对9.20±2.973；t值=0.001；95%置信区间2.480 - 4.920）。研究结束访视时的爱丁堡产后抑郁评分具有统计学意义（11.05±3.839对10.24±3.872；t值=0.008；95%置信区间 - 1.40至 - 0.213）。教育程度、收入、婚姻持续时间、体重指数和自杀意念是本研究中确定的一些导致孕妇抑郁的预测因素。
该研究结果表明孕妇抑郁症状在临床上有显著增加。建议在孕期进行常规心理筛查和干预。
