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肿瘤标志物在长期生存的巨大纵隔内胚窦瘤中的诊断和预后价值:根治性切除术后12年随访

The diagnostic and prognostic value of tumor markers in giant mediastinal endodermal sinus tumor with prolonged survival: Twelve-year follow up after radical resection.

作者信息

Al Ghamdi Abdullah M, Al Fraih Othman M, Al Abdulhai Meenal A, Alshaer Ahmed, Al Qahtani Yousif, Khan Natasha T, Chaudhry Ikram Ul Haq

机构信息

Department of Thoracic Surgery, Dammam Medical Complex Saudi Arabia, Saudi Arabia.

出版信息

Ann Med Surg (Lond). 2021 Aug 23;69:102744. doi: 10.1016/j.amsu.2021.102744. eCollection 2021 Sep.

DOI:10.1016/j.amsu.2021.102744
PMID:34484723
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8390953/
Abstract

We report a case of 16 -year male who presented with nonproductive cough, chest pain, and hemoptysis. His chest -x-ray and computerized tomographic scan (CT) of the thorax with contrast enhancement revealed a large mediastinal mass mostly occupying the left hemithorax. Percutaneous CT scan-guided biopsy of the mediastinal mass was reported as an endodermal sinus tumor (EDST). Serum alpha-fetoprotein levels were markedly raised (120,000 ng/ml). After completion of chemotherapy repeat, CT scan of the thorax revealed a large residual mass. Radical resection of the tumor was carried out. Twelve-year post-surgical resection follow-up with serial serum alpha-fetoprotein (AFP) tumor marker levels and CT scan of the thorax showed no recurrence.

摘要

我们报告一例16岁男性患者,其症状为干咳、胸痛和咯血。他的胸部X光片及胸部增强计算机断层扫描(CT)显示一个巨大的纵隔肿块,大部分占据左半胸。经皮CT引导下纵隔肿块活检报告为内胚窦瘤(EDST)。血清甲胎蛋白水平显著升高(120,000 ng/ml)。化疗结束后复查胸部CT,显示有一个大的残留肿块。遂进行了肿瘤根治性切除术。术后12年随访,连续检测血清甲胎蛋白(AFP)肿瘤标志物水平并进行胸部CT扫描,结果显示无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c16/8390953/81fa69de9742/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c16/8390953/81fa69de9742/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c16/8390953/81fa69de9742/gr1.jpg

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本文引用的文献

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Int J Clin Exp Pathol. 2020 Nov 1;13(11):2772-2777. eCollection 2020.
2
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
3
Mediastinal endodermal sinus tumor associated with fatal hemophagocytic syndrome.
Hematol Oncol Stem Cell Ther. 2011;4(3):138-41. doi: 10.5144/1658-3876.2011.138.
4
Intensive chemotherapy and radical resections for primary nonseminomatous mediastinal germ cell tumors.
Ann Thorac Surg. 2000 Feb;69(2):337-43; discussion 343-4. doi: 10.1016/s0003-4975(99)01472-1.
5
Results of treatment after relapse from high-dose chemotherapy in germ cell tumors.生殖细胞肿瘤大剂量化疗复发后的治疗结果。
J Clin Oncol. 2000 Mar;18(6):1181-6. doi: 10.1200/JCO.2000.18.6.1181.
6
Primary mediastinal nonseminomatous germ cell tumors: the influence of postchemotherapy pathology on long-term survival after surgery.原发性纵隔非精原细胞性生殖细胞肿瘤:化疗后病理对手术后长期生存的影响。
J Thorac Cardiovasc Surg. 1999 Oct;118(4):692-700. doi: 10.1016/S0022-5223(99)70015-2.
7
Primary germ cell tumors of the mediastinum: III. Yolk sac tumor, embryonal carcinoma, choriocarcinoma, and combined nonteratomatous germ cell tumors of the mediastinum--a clinicopathologic and immunohistochemical study of 64 cases.纵隔原发性生殖细胞肿瘤:III. 纵隔卵黄囊瘤、胚胎性癌、绒毛膜癌及非畸胎瘤性生殖细胞肿瘤的联合——64例临床病理及免疫组化研究
Cancer. 1997 Aug 15;80(4):699-707.
8
Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging.纵隔原发性生殖细胞肿瘤:I. 322例分析,特别关注畸胎瘤样病变并提出组织病理学分类和临床分期建议
Cancer. 1997 Aug 15;80(4):681-90.
9
Endodermal sinus (yolk sac) tumors of the anterior mediastinum.
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10
Yolk sac tumor (endodermal sinus tumor) and alpha-fetoprotein. A report of three cases.卵黄囊瘤(内胚窦瘤)与甲胎蛋白。三例报告。
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