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拔牙后出血:着重于罕见凝血障碍的诊断。

Post-dental extraction bleeding: Emphasis on the diagnosis of rare coagulation disorders.

作者信息

Shadamarshan R Arunkumar, Sharma Rohit, Pradhan Ishan, Kumar Pramod

机构信息

Dental Centre, C/o WLDMH HQ IMTRAT Bhutan.

Command Military Dental Centre (WC) Chandimandir India.

出版信息

Clin Case Rep. 2021 Aug 30;9(9):e04746. doi: 10.1002/ccr3.4746. eCollection 2021 Sep.

DOI:10.1002/ccr3.4746
PMID:34484775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8405522/
Abstract

Disorders of the fibrin stabilizing and fibrinolytic pathway should be considered in patients with excessive postsurgical bleeding with normal screening tests of hemostasis. History, clinical assessment of the timing and severity of bleeding along with utilization of advanced tests such as global hemostasis assays and appropriate coagulation factor assays (especially FXIII) will aid in the diagnosis.

摘要

对于术后出血过多但止血筛查试验正常的患者,应考虑纤维蛋白稳定和纤维蛋白溶解途径紊乱。病史、对出血时间和严重程度的临床评估,以及使用如整体止血检测和适当的凝血因子检测(特别是FXIII)等先进检测方法,将有助于诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9832/8405522/d36819ef9b9b/CCR3-9-e04746-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9832/8405522/d36819ef9b9b/CCR3-9-e04746-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9832/8405522/d36819ef9b9b/CCR3-9-e04746-g001.jpg

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1
Post-dental extraction bleeding: Emphasis on the diagnosis of rare coagulation disorders.拔牙后出血:着重于罕见凝血障碍的诊断。
Clin Case Rep. 2021 Aug 30;9(9):e04746. doi: 10.1002/ccr3.4746. eCollection 2021 Sep.
2
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本文引用的文献

1
Inherited disorders of the fibrinolytic pathway.纤维蛋白溶解途径的遗传性疾病。
Transfus Apher Sci. 2019 Oct;58(5):572-577. doi: 10.1016/j.transci.2019.08.007. Epub 2019 Aug 8.
2
Acquired factor XIII deficiency: A review.获得性因子 XIII 缺乏症:综述
Transfus Apher Sci. 2018 Dec;57(6):724-730. doi: 10.1016/j.transci.2018.10.013. Epub 2018 Oct 30.
3
Factor XIII deficiency diagnosis: Challenges and tools.因子 XIII 缺乏症的诊断:挑战与工具。
Int J Lab Hematol. 2018 Feb;40(1):3-11. doi: 10.1111/ijlh.12756. Epub 2017 Oct 13.
4
Minimal factor XIII activity level to prevent major spontaneous bleeds.预防自发性大出血的最小因子 XIII 活性水平。
J Thromb Haemost. 2017 Sep;15(9):1728-1736. doi: 10.1111/jth.13772. Epub 2017 Aug 17.
5
Dental Management of a Child with Incidentally Detected Hemophilia: Report of a Clinical Case.一名偶然发现患有血友病儿童的牙科治疗管理:临床病例报告
Case Rep Dent. 2017;2017:7429738. doi: 10.1155/2017/7429738. Epub 2017 May 28.
6
Effects of Factor XIII Deficiency on Thromboelastography. Thromboelastography with Calcium and Streptokinase Addition is more Sensitive than Solubility Tests.因子 XIII 缺乏对血栓弹力图的影响。添加钙和链激酶的血栓弹力图比溶解度试验更敏感。
Mediterr J Hematol Infect Dis. 2016 Aug 16;8(1):e2016037. doi: 10.4084/MJHID.2016.037. eCollection 2016.
7
Recommendation for ISTH/SSC Criterion 2015 for autoimmune acquired factor XIII/13 deficiency.关于2015年国际血栓与止血学会/科学标准化委员会自身免疫性获得性因子XIII/13缺乏症标准的建议。
Thromb Haemost. 2016 Sep 27;116(4):772-774. doi: 10.1160/TH16-05-0362. Epub 2016 Jul 21.
8
Guidelines for laboratory diagnosis of factor XIII deficiency.凝血因子XIII缺乏症的实验室诊断指南。
Blood Coagul Fibrinolysis. 2016 Jun;27(4):361-4. doi: 10.1097/MBC.0000000000000459.
9
Thromboelastography: A Practice Summary for Nurse Practitioners Treating Hemorrhage.
J Nurse Pract. 2015 Jul-Aug;11(7):702-709. doi: 10.1016/j.nurpra.2015.05.006.
10
Factor XIII: congenital deficiency factor XIII, acquired deficiency, factor XIII A-subunit, and factor XIII B-subunit.凝血因子 XIII:先天性凝血因子 XIII 缺乏症,获得性凝血因子 XIII 缺乏症,凝血因子 XIII A 亚单位,和凝血因子 XIII B 亚单位。
Arch Pathol Lab Med. 2014 Feb;138(2):278-81. doi: 10.5858/arpa.2012-0639-RS.