Shah Sangam, Ojha Rajeev, Sitaula Sanjeeta, Regmi Dosti, Karn Ragesh, Gajurel Bikram Prasad, Rajbhandari Reema, Gautam Niraj, Paudel Sunanda, Shrestha Aashish
Maharajgunj Medical Campus, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal.
Department of Neurology, Tribhuvan University Institute of Medicine, Maharajgunj, Kathmanadu 44600, Nepal.
Case Rep Neurol Med. 2021 Aug 26;2021:8100423. doi: 10.1155/2021/8100423. eCollection 2021.
Neuromyelitis optica spectrum disorder (NMOSD) is an immune-mediated inflammatory condition involving spinal cord and optic nerves. Diagnosis of NMOSD is done by aquaporin-4 antibody (AQP4) in patients with optic neuritis. Myelin oligodendrocyte glycoprotein (MOG) expressed on the oligodendrocyte cell surface and on the outermost cell surface of the myelin sheath may also be present in patients with NMOSD bilateral optic neuritis. Here, we describe a case of a thirty-nine-year-old-female with recurrent bilateral optic neuritis with positive anti-MOG antibody, and anti-MOG syndrome has not previously been reported from Nepal.
视神经脊髓炎谱系障碍（NMOSD）是一种涉及脊髓和视神经的免疫介导的炎症性疾病。视神经炎患者通过水通道蛋白4抗体（AQP4）进行NMOSD的诊断。少突胶质细胞表面和髓鞘最外层细胞表面表达的髓鞘少突胶质细胞糖蛋白（MOG）在NMOSD双侧视神经炎患者中也可能存在。在此，我们描述了一例39岁女性复发性双侧视神经炎且抗MOG抗体阳性的病例，尼泊尔此前尚未报道过抗MOG综合征。
