Brinkman D J, Brand H S, Rademacher W H M, Bots C P, Rozema F R
Ned Tijdschr Tandheelkd. 2021 Sep;128(9):441-450. doi: 10.5177/ntvt.2021.09.21068.
To alleviate acute dental pain, dentists and dental specialists frequently prescribe analgesics to patients, either on prescription or not. In order to effectively manage dental pain, it is advisable to follow a step-by-step plan based on the WHO analgesic ladder: step 1, start with acetaminophen step 2, add an NSAID (e.g. ibuprofen, diclofenac, naproxen); step 3, add a weak opioid (e.g. tramadol) in combination with acetaminophen or an NSAID; step 4, replace a weak opioid with a strong opioid (e.g. morphine or oxycodone). A dentist in general practice or a dental specialist needs to know, the mechanism of action and the most important interactions, contraindications and adverse effects of each of these groups of medications. Attention is needed when prescribing analgesics to risk groups such as frail elderly, pregnant and lactating women, and children.
为缓解急性牙痛,牙医和牙科专家经常给患者开止痛药,无论是否凭处方。为有效控制牙痛,建议遵循基于世界卫生组织止痛阶梯的逐步计划:第一步,从对乙酰氨基酚开始;第二步,添加一种非甾体抗炎药(如布洛芬、双氯芬酸、萘普生);第三步,添加一种弱阿片类药物(如曲马多)并与对乙酰氨基酚或一种非甾体抗炎药联合使用;第四步,用强阿片类药物(如吗啡或羟考酮)替代弱阿片类药物。普通牙科医生或牙科专家需要了解这些药物组中每种药物的作用机制以及最重要的相互作用、禁忌症和不良反应。给体弱的老年人、孕妇和哺乳期妇女以及儿童等风险人群开止痛药时需要格外注意。