Ferreira Lara, Amaral Raquel, Gomes Fernanda, Cabral José
Department of Paediatrics, Hospital Divino Espírito Santo, Ponta Delgada, Portugal.
Department of Paediatrics, Section of Paediatric Gastroenterology, Centro Hospitalar Universitário de Lisboa Central, Hospital Dona Estefânia, Lisbon, Portugal.
Paediatr Int Child Health. 2021 Nov;41(4):291-294. doi: 10.1080/20469047.2021.1890681. Epub 2021 Sep 7.
A 7-month-old boy was admitted with acute gastro-enteritis accompanied by fever and hyponatraemic dehydration. The clinical course was complicated by severe hypokalaemia and hypo-albuminaemia with anasarca. Protein-losing enteropathy (PLE) owing to colitis was diagnosed and was complicated by fungal sepsis owing to . Colonoscopy demonstrated multiple diffuse ulcers and sub-epithelial haemorrhages extending from the rectum to the hepatic angle. He required prolonged nutritional support comprising partial parenteral feeding for 10 days, followed by a hypo-allergenic diet until 13 months of age when cow milk was tolerated. He was discharged on a normal diet and in good health at 19 months of age. AVPU scale: A alert, V verbally responsive, P painfully responsive, U unresponsive; CMV: cytomegalovirus; EBV: Epstein-Barr virus; HIV: human immunodeficiency virus; Ig: immunoglobulin; IBD: inflammatory bowel disease; IPEX: immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome; PICU: paediatric intensive care unit; PLE: protein-losing enteropathy.
一名7个月大的男童因急性胃肠炎伴发热及低钠血症性脱水入院。临床过程中出现严重低钾血症和低白蛋白血症并伴有全身水肿。诊断为因结肠炎导致的蛋白丢失性肠病（PLE），并因……并发真菌败血症。结肠镜检查显示从直肠至肝曲有多发性弥漫性溃疡和上皮下出血。他需要长期的营养支持，包括10天的部分胃肠外营养，随后是低敏饮食，直到13个月大时能够耐受牛奶。他在19个月大时以正常饮食且健康状况良好出院。AVPU量表：A清醒，V对言语有反应，P对疼痛有反应，U无反应；CMV：巨细胞病毒；EBV：EB病毒；HIV：人类免疫缺陷病毒；Ig：免疫球蛋白；IBD：炎症性肠病；IPEX：免疫失调、多内分泌病、肠病、X连锁综合征；PICU：儿科重症监护病房；PLE：蛋白丢失性肠病。
