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美国皮肤肿瘤医学管理(USCOM):实用算法。

US Cutaneous Oncodermatology Management (USCOM): A Practical Algorithm.

出版信息

J Drugs Dermatol. 2021 Sep 1;20(9):3ss-s19. doi: 10.36849/jdd.6229.

Abstract

BACKGROUND

An increasing number of patients survive or are living with cancer. Anticancer treatments frequently have cutaneous adverse events (cAEs) that may severely impact patients' quality of life and interrupt anticancer treatment. The US Cutaneous Oncodermatology Management (USCOM) project aims to improve cancer patients' and survivors' quality of life by offering tools for preventing and managing cAEs.

METHODS

An algorithm was designed to reduce the incidence of cAEs, treat cAEs, and maintain healthy skin using general measures and over-the-counter agents to support all healthcare providers treating oncology patients, including physicians, nurses, pharmacists, and advanced providers. The panel used a modified Delphi approach, developed, discussed, and reached a consensus on statements and an evidence-based algorithm.

RESULTS

The USCOM algorithm includes education on cAEs for patients and clinicians supporting prevention, treatment, and maintenance using skincare measures before, during, and after cancer treatment. A skincare regimen including hygiene, moisturization, and sun protection products should be safe and effective in helping to minimize cAEs and improving skin conditions such as erythema, xerosis, pruritus, and photosensitivity. The number and quality of studies evaluating skincare formulations and regimens for cAEs are increasing, but the evidence on the benefits of specific formulations is still scarce.

CONCLUSIONS

The algorithm focuses on general measures and skincare to prevent or reduce the severity of cAEs. Increased awareness of cAEs by the multidisciplinary team treating and guiding the cancer patient throughout their care may improve patient outcomes. J Drugs Dermatol. 2021;20:9(Suppl):s3-19.

摘要

背景

越来越多的癌症患者幸存或存活。抗癌治疗常伴有皮肤不良反应(cAEs),这可能严重影响患者的生活质量并中断抗癌治疗。美国皮肤肿瘤医学管理(USCOM)项目旨在通过提供预防和管理 cAEs 的工具来提高癌症患者和幸存者的生活质量。

方法

设计了一种算法,以减少 cAEs 的发生率、治疗 cAEs 并通过一般措施和非处方药物来保持皮肤健康,以支持所有治疗肿瘤患者的医疗保健提供者,包括医生、护士、药剂师和高级提供者。专家组采用改良 Delphi 方法,开发、讨论并就声明和基于证据的算法达成共识。

结果

USCOM 算法包括对患者和临床医生进行 cAEs 教育,以支持预防、治疗和维持,在癌症治疗之前、期间和之后使用皮肤护理措施。皮肤护理方案包括卫生、保湿和防晒产品,应该安全有效,有助于最大限度地减少 cAEs 并改善皮肤状况,如红斑、干燥、瘙痒和光敏感性。评估 cAEs 皮肤护理配方和方案的研究数量和质量都在增加,但关于特定配方益处的证据仍然稀缺。

结论

该算法侧重于一般措施和皮肤护理,以预防或减少 cAEs 的严重程度。治疗和指导癌症患者整个护理过程的多学科团队对 cAEs 的认识提高,可能会改善患者的结局。J 皮肤病药物学杂志。2021;20:9(增刊):s3-19。

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