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NECASA I:北欧国家痤疮患者皮肤护理管理中的实用算法。

NECASA I: A Practical Algorithm Integrating Skincare in the Management of Acne Patients in the Nordic European Countries.

出版信息

J Drugs Dermatol. 2024 Sep 1;23(9):782-788. doi: 10.36849/JDD.8472.

DOI:10.36849/JDD.8472
PMID:39231071
Abstract

BACKGROUND

Acne vulgaris is a multifactorial dermatosis primary of the face and trunk. Erythema, pruritus, and xerosis are frequent adverse effects of first-line acne treatment and, if not appropriately counseled and managed, can exacerbate, leading to regimen nonadherence and poor outcomes.

METHODS

A panel of 6 dermatologists (five from the Nordic European Countries and one from the UK) employed a modified Delphi method and reached a consensus on a practical acne treatment and maintenance algorithm integrating skincare based on the best available evidence, and the panels' clinical experience, and opinions.

RESULTS

The Nordic European Countries Acne Skincare Algorithm (NECASA) recommends integrating skincare and nonprescription acne treatment into acne regimens, addressing the relative lack of standardized guidance on their use as mono or adjunctives to acne treatment. The algorithm uses stratification by acne subtype and discusses management approaches per type of acne (comedonal, papulopustular, and nodulocystic acne), severity (mild to moderate and severe), and maintenance treatment. Skincare monotherapy may reduce acne lesions and maintain clearance in patients with mild acne. Adjunctive skincare may enhance the efficacy and improve tolerability of acne treatment, reduce pigmentary alterations, and improve skin barrier function.

CONCLUSIONS

The NECASA algorithm may serve as a roadmap for integrating skincare in managing acne patients and tailoring acne treatment to improve adherence and tolerance to treatment and patient outcomes. J Drugs Dermatol. 2024;23(9):782-788. doi:10.36849/JDD.8472.

摘要

背景

寻常痤疮是一种多因素的皮肤疾病,主要发生在面部和躯干。红斑、瘙痒和干燥是痤疮一线治疗的常见不良反应,如果没有得到适当的咨询和管理,可能会加重病情,导致治疗方案不遵守和治疗效果不佳。

方法

由 6 名皮肤科医生(5 名来自北欧国家,1 名来自英国)组成的专家组采用改良 Delphi 方法,根据最佳现有证据、专家组的临床经验和意见,就整合皮肤护理的痤疮治疗和维持方案达成共识。

结果

北欧国家痤疮皮肤护理算法(NECASA)建议将皮肤护理和非处方痤疮治疗纳入痤疮治疗方案,以解决在使用这些方法作为痤疮治疗的单一或辅助治疗时缺乏标准化指导的问题。该算法根据痤疮亚型进行分层,并根据痤疮类型(粉刺性、丘疹脓疱性和结节囊肿性痤疮)、严重程度(轻度至中度和重度)和维持治疗来讨论管理方法。皮肤护理单药治疗可能会减少轻度痤疮患者的痤疮病变并维持缓解。辅助性皮肤护理可能会增强痤疮治疗的疗效,提高治疗的耐受性,减少色素改变,并改善皮肤屏障功能。

结论

NECASA 算法可以作为管理痤疮患者时整合皮肤护理的路线图,并针对特定患者调整痤疮治疗方案,以提高治疗方案的依从性和耐受性,改善患者的治疗效果。J 皮肤病药物治疗杂志。2024;23(9):782-788. doi:10.36849/JDD.8472.

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