Kou Ren-Zhong, Yang Feng, Lin Qi, Tao La-Mei, Yu Xiao-Lu, Hou Teng, Wang Lin, Fan Gang-Qi
Department of Encephalopathy, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing 210000, Jiangsu Province, China.
Department of TCM, Zhongshan Hospital Affiliated to Fudan University.
Zhongguo Zhen Jiu. 2021 Sep 12;41(9):993-6. doi: 10.13703/j.0255-2930.20201203-k0007.
To observe the therapeutic effect of horizontal penetration needling combined with rizatriptan monobenzoate tablets, simple horizontal penetration needling and simple rizatriptan monobenzoate tablets for migraine without aura in acute stage.
A total of 99 patients with migraine without aura in acute stage were randomized into an acupuncture plus medication group, an acupuncture group and a western medication group, 33 cases in each one. In the acupuncture group, horizontal penetration needling was applied once at Hanyan (GB 4) to Xuanli(GB 6), Shenting (GV 24) to Yintang (GV 29), Baihui (GV 20) to Qianding (GV 21), etc. for 2 h. In the western medication group, oral rizatriptan monobenzoate tablets for 10 mg were given once. In the acupuncture plus medication group, treatment of acupuncture combined with rizatriptan monobenzoate tablets were given, the application was the same as the acupuncture group and the western medication group. Before treatment and 0.5, 2, 24 h after treatment, the visual analogue scale (VAS) score was observed, the remission rate and the disappearance rate of migraine of 2, 24 h after treatment were compared in the 3 groups.
Compared before treatment, the VAS scores of each time point after treatment were decreased in the 3 groups (<0.05), and the changes in the acupuncture plus medication group were greater than those in the acupuncture group and the western medication group (<0.05). The remission rates of 24 h after treatment and the disappearance rates of migraine of 2, 24 h after treatment in the acupuncture plus medication group were higher than those in the acupuncture group and the western medication group (<0.05).
Horizontal penetration needling combined with rizatriptan monobenzoate tablets have significant therapeutic effect on rapid analgesia and continuous analgesia for migraine without aura in acute stage, its effect is superior to simple horizontal penetration needling and simple rizatriptan monobenzoate tablets.
观察透刺法联合苯甲酸利扎曲普坦片、单纯透刺法及单纯苯甲酸利扎曲普坦片治疗急性期无先兆偏头痛的疗效。
将99例急性期无先兆偏头痛患者随机分为针药组、针刺组和西药组，每组33例。针刺组采用透刺法，如颔厌（GB 4）透悬厘（GB 6）、神庭（GV 24）透印堂（GV 29）、百会（GV 20）透前顶（GV 21）等，留针2小时。西药组口服10mg苯甲酸利扎曲普坦片1次。针药组采用针刺联合苯甲酸利扎曲普坦片治疗，针刺方法同针刺组，药物应用同西药组。分别于治疗前及治疗后0.5、2、24小时观察视觉模拟评分（VAS），比较3组治疗后2、24小时偏头痛的缓解率及消失率。
与治疗前比较，3组治疗后各时间点VAS评分均降低（P<0.05），且针药组变化幅度大于针刺组和西药组（P<0.05）。针药组治疗后24小时缓解率及治疗后2、24小时偏头痛消失率均高于针刺组和西药组（P<0.05）。
透刺法联合苯甲酸利扎曲普坦片治疗急性期无先兆偏头痛在快速止痛及持续镇痛方面疗效显著，效果优于单纯透刺法及单纯苯甲酸利扎曲普坦片。
