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Myosin Modulation in Hypertrophic Cardiomyopathy and Systolic Heart Failure: Getting Inside the Engine.

作者信息

Daniels Matthew J, Fusi Luca, Semsarian Christopher, Naidu Srihari S

机构信息

Manchester Heart Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, United Kingdom (M.J.D.).

Division of Cardiovascular Sciences, Manchester Academic Health Sciences Center (M.J.D.), University of Manchester, Manchester, United Kingdom.

出版信息

Circulation. 2021 Sep 7;144(10):759-762. doi: 10.1161/CIRCULATIONAHA.121.056324.

DOI:10.1161/CIRCULATIONAHA.121.056324
PMID:34491773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7611636/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d0/7611636/471d800f56a4/EMS132025-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d0/7611636/471d800f56a4/EMS132025-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d0/7611636/471d800f56a4/EMS132025-f001.jpg

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N Engl J Med. 2021 Jan 14;384(2):105-116. doi: 10.1056/NEJMoa2025797. Epub 2020 Nov 13.
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Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.马卡丹特治疗有症状梗阻性肥厚型心肌病(EXPLORER-HCM)的随机、双盲、安慰剂对照、3 期临床试验
Lancet. 2020 Sep 12;396(10253):759-769. doi: 10.1016/S0140-6736(20)31792-X. Epub 2020 Aug 29.
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BMC Cardiovasc Disord. 2024 Apr 5;24(1):197. doi: 10.1186/s12872-024-03861-8.
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Am J Cardiovasc Drugs. 2023 Sep;23(5):519-532. doi: 10.1007/s40256-023-00599-0. Epub 2023 Aug 1.
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