Department of Neurology, The 910th Hospital of the Joint Logistics Support Force of the Chinese PLA, Quanzhou, Fujian.
Department of Neurology, Hebei General Hospital.
Neurologist. 2021 Sep 7;26(5):172-174. doi: 10.1097/NRL.0000000000000334.
Mild encephalopathy with a reversible splenial lesion (MERS) is a clinical-radiologic syndrome presenting with a reversible lesion in the splenium of the corpus callosum. MERS is associated with many potential etiologies, including cytomegalovirus (CMV) infection in children. We report an adult patient with CMV-associated MERS.
A previously healthy 25-year-old man was admitted with a 4-day history of fever, headache, and vomiting. Brain magnetic resonance imaging demonstrated an isolated lesion of the splenium of the corpus callosum with hyperintensity on T2 and diffusion-weighted sequences and reduced values on apparent diffusion coefficient maps. High throughput gene detection for pathogens in cerebrospinal fluid revealed infection with CMV. The splenial lesion resolved 4 weeks after onset.
This is the first report an adult patient with CMV-associated MERS. Recognition of this clinical-radiologic syndrome can guide diagnosis and management.
轻度脑炎伴胼胝体压部病变（MERS）是一种临床-影像学综合征，表现为胼胝体压部的可逆性病变。MERS 与许多潜在病因相关，包括儿童巨细胞病毒（CMV）感染。我们报告一例 CMV 相关性 MERS 的成年患者。
一名既往健康的 25 岁男性，因发热、头痛和呕吐 4 天入院。脑磁共振成像显示胼胝体压部孤立性病变，T2 和弥散加权序列呈高信号，表观弥散系数图上值降低。对脑脊液病原体的高通量基因检测显示 CMV 感染。压部病变在发病后 4 周消退。
这是首例 CMV 相关性 MERS 的成年患者报告。认识到这种临床-影像学综合征可以指导诊断和治疗。
