Yang Chuntian, Wang Qingfu, Ren Yibin, Jin Daiqiang, Liu Dan, Moradi Masoumeh, Chen Xiaobo, Li Huabing, Xu Dake, Wang Fuhui
Shenyang National Laboratory for Materials Science, Northeastern University, Shenyang 110819, China.
School of Stomatology, China Medical University, Shenyang 110001, China.
Bioelectrochemistry. 2021 Dec;142:107940. doi: 10.1016/j.bioelechem.2021.107940. Epub 2021 Aug 26.
High nitrogen nickel-free austenitic stainless steels (HNSs) have great potentials to be used in dentistry owing to its exceptional mechanical properties, high corrosion resistance, and biocompatibility. In this study, HNSs with nitrogen of 0.88 wt% and 1.08 wt% displayed much lower maximum pit depths than 316L stainless steel (SS) after 21 d of immersion in abiotic artificial saliva (2.2 μm and 1.7 μm vs. 4.5 μm). Microbiologically influenced corrosion (MIC) evaluations revealed that Streptococcus mutans biofilms led to much severer corrosion of 316L SS than HNSs. Corrosion current densities of HNSs were two orders of magnitude lower than that of 316L SS after incubation of 7 d (37.5 nA/cm and 29.9 nA/cm vs. 5.63 μA/cm). The pitting potentials of HNSs were at least 550 mV higher than that of 316L SS in the presence of S. mutans, confirming the better MIC resistance of HNSs. Cytotoxicity assay confirmed that HNSs were not toxic to MC3T3-E1 cells and allowed better sessile cell growth on them than on 316L SS. It can be concluded that HNSs are more suitable dental materials than the conventional 316L SS.
高氮无镍奥氏体不锈钢(HNSs)因其优异的机械性能、高耐腐蚀性和生物相容性,在牙科领域具有巨大的应用潜力。在本研究中,含氮量为0.88 wt%和1.08 wt%的HNSs在非生物人工唾液中浸泡21天后,其最大点蚀深度远低于316L不锈钢(SS)(分别为2.2μm和1.7μm,而316L不锈钢为4.5μm)。微生物影响腐蚀(MIC)评估表明,变形链球菌生物膜对316L SS的腐蚀比HNSs严重得多。培养7天后,HNSs的腐蚀电流密度比316L SS低两个数量级(分别为37.5 nA/cm和29.9 nA/cm,而316L不锈钢为5.63 μA/cm)。在存在变形链球菌的情况下,HNSs的点蚀电位比316L SS至少高550 mV,证实了HNSs具有更好的抗MIC性能。细胞毒性试验证实,HNSs对MC3T3-E1细胞无毒,并且与316L SS相比,能使贴壁细胞在其上更好地生长。可以得出结论,与传统的316L SS相比,HNSs是更适合的牙科材料。