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前置胎盘伴第一 trimester 难免流产的 Rh 阴性孕妇:1 例报告。

Placenta increta presenting with threatened miscarriage during the first trimester in rhesus-negative mother: a case report.

机构信息

Department of Obstetrics & Gynaecology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

出版信息

J Med Case Rep. 2021 Sep 8;15(1):448. doi: 10.1186/s13256-021-03030-x.

DOI:10.1186/s13256-021-03030-x
PMID:34493340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8424964/
Abstract

BACKGROUND

Placenta accreta is known to be associated with significant maternal morbidity and mortality-primarily due to intractable bleeding during abortion or delivery at any level of gestation. The complications could be reduced if placenta accreta is suspected in a patient with a history of previous cesarean delivery and the gestational sac/placenta is located at the lower part of the uterus. Then, a proper management plan can be instituted, and complications can be reduced. The diagnosis of placenta accreta in the first trimester of pregnancy is considered uncommon.

CASE PRESENTATION

A 34-year-old Malay, gravida 4, para 3, rhesus-negative woman was referred from a private hospital at 13 weeks owing to accreta suspicion for further management. She has a history of three previous lower-segment cesarean sections. She also had per vaginal bleeding in the early first trimester, which is considered to indicate threatened miscarriage. Transabdominal ultrasound revealed features consistent with placenta accreta spectrum. She was counseled for open laparotomy and hysterectomy because of potential major complication if she continued with the pregnancy. Histopathological examination revealed placenta increta.

CONCLUSION

A high index of suspicion of placenta previa accreta must be in practice in a patient with a history of previous cesarean deliveries and low-lying placenta upon ultrasound examination during early gestation.

摘要

背景

胎盘植入已知与显著的产妇发病率和死亡率相关 - 主要是由于在任何妊娠水平的流产或分娩期间出现难以控制的出血。如果在有既往剖宫产史且妊娠囊/胎盘位于子宫下段的患者中怀疑存在胎盘植入,则可以减少并发症。然后,可以制定适当的管理计划,并减少并发症。在妊娠早期诊断胎盘植入被认为并不常见。

病例介绍

一名 34 岁的马来族妇女,第 4 次妊娠,第 3 次分娩,Rh 阴性,因疑似植入物而从私立医院转诊至我院,以进行进一步管理。她有三次既往下段剖宫产史。她还在孕早期出现过阴道出血,这被认为是先兆流产的迹象。经腹超声显示符合胎盘植入谱系的特征。由于如果继续妊娠可能会出现潜在的严重并发症,她被建议行剖腹手术和子宫切除术。组织病理学检查显示胎盘植入。

结论

在有既往剖宫产史和超声检查在孕早期显示胎盘位置较低的患者中,必须高度怀疑胎盘前置植入。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/52f50d56896a/13256_2021_3030_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/87c849d5a838/13256_2021_3030_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/fa2230c555d3/13256_2021_3030_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/4d8560749a27/13256_2021_3030_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/52f50d56896a/13256_2021_3030_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/87c849d5a838/13256_2021_3030_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/fa2230c555d3/13256_2021_3030_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/4d8560749a27/13256_2021_3030_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/8424964/52f50d56896a/13256_2021_3030_Fig4_HTML.jpg

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本文引用的文献

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First-trimester abortion complicated with placenta accreta: A systematic review.孕早期流产合并胎盘植入:一项系统综述。
Taiwan J Obstet Gynecol. 2019 Jan;58(1):10-14. doi: 10.1016/j.tjog.2018.11.032.
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Pathophysiology of Placenta Accreta Spectrum Disorders: A Review of Current Findings.胎盘植入谱系疾病的病理生理学:当前研究结果综述
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Screening for morbidly adherent placenta in early pregnancy.早孕期凶险性前置胎盘的筛查。
Ultrasound Obstet Gynecol. 2019 Jan;53(1):101-106. doi: 10.1002/uog.20104. Epub 2018 Sep 10.
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Study of the utility and problems of common iliac artery balloon occlusion for placenta previa with accreta.前置胎盘合并植入患者髂总动脉球囊阻断术的应用及问题研究
J Obstet Gynaecol Res. 2018 Mar;44(3):456-462. doi: 10.1111/jog.13550. Epub 2018 Jan 3.
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Changes in ultrasonography indicators of abnormally invasive placenta during pregnancy.妊娠期胎盘植入异常的超声检查指标变化
Int J Gynaecol Obstet. 2018 Mar;140(3):319-325. doi: 10.1002/ijgo.12413. Epub 2018 Jan 9.
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Incidence, risk factors and perinatal outcomes for placenta accreta in Australia and New Zealand: a case-control study.澳大利亚和新西兰胎盘植入的发病率、危险因素及围产期结局:一项病例对照研究。
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First-trimester detection of abnormally invasive placenta in high-risk women: systematic review and meta-analysis.早孕期高危孕妇异常侵袭性胎盘的检测:系统评价和荟萃分析。
Ultrasound Obstet Gynecol. 2018 Feb;51(2):176-183. doi: 10.1002/uog.18840.
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Prenatal ultrasound diagnosis and outcome of placenta previa accreta after cesarean delivery: a systematic review and meta-analysis.剖宫产术后胎盘植入的产前超声诊断及结局:一项系统评价与荟萃分析
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